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Zanaflex (Tizanidine)

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Zanaflex is used to relieve the spasms and increased muscle tone caused by multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control), stroke.

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Also known as: Tizanidine


Generic Zanaflex is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Generic Zanaflex has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Generic Zanaflex are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. The imidazoline chemical structure of Generic Zanaflex is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Generic Zanaflex was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure. Zanaflex is also known as Tizanidine, Sirdalud. Generic name of Generic Zanaflex is Tizanidine-Oral. Brand name of Generic Zanaflex is Zanaflex.


You should take it by mouth. It usually is taken two or three times a day. If you want to achieve most effective results do not stop taking Generic Zanaflex suddenly.


If you overdose Generic Zanaflex and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zanaflex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Zanaflex if you are allergic to Generic Zanaflex components. Do not take Generic Zanaflex if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Generic Zanaflex if you have liver disease, have kidney disease, have low blood pressure. Be careful with Generic Zanaflex if you are taking medication to treat high blood pressure or birth control pills. Avoid alcohol. Do not stop take it suddenly.

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Study of beta endorphin metabolism in inflamed tissue, serum and trypsin solution by liquid chromatography-tandem mass spectrometric analysis. Accumulated evidence suggests a major role for the activation of the Sonic Hedgehog (SHH) signaling pathway in the development of neural crest stem cells that give rise to the sympathetic nervous system. Combinatorial ART decreases HIV replication, thus reducing rates of virus transmission. The flavoprotein Cyc2p, a mitochondrial cytochrome c assembly factor, is a NAD(P)H-dependent haem reductase. Treatment with cortisone of pleural exudative processes in the course of pulmonary tuberculosis. Agonists of glutamate ionotropic (NMDA) and metabotropic receptors (mGluRI and mGluRIII) had the regulatory effect on ADP-ribosyl cyclase/CD38 activity in cerebellar granular cells of newborn rats. Diversity and plasticity of microglial cells in psychiatric and neurological disorders. Twelve Chinese immature piglets were induced acute lung what is generic claritin injury by OA. Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973.

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Promoting Self-Management in Primary Care - the Association of Motivation for Change, Self-Efficacy and Psychological Distress Prior to the Onset of Intervention. Eliminating or diminishing risk behaviors that lead to cardiovascular diseases could be achieved through primary prevention during the general practice visits. Overall, the shockwave therapy on muscles represents a confirmation and extension of the existing trigger point therapy. The theoretical pI of the mature peptide is 6.09, which suggests that it is an anionic molecule. Spontaneous retroclival hematoma in pituitary apoplexy: case series. Biopharmaceutical process development - shortcut to market: an interview with Rolf Werner from Boehringer Ingelheim. Pain-related middle-latency somatosensory evoked potentials in the prognosis of post anoxic coma: a preliminary report.

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