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Sulphatrim (Trimethoprim)

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Sulphatrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Actrim, Altavit, Bactelan, Bacterol, Bactricid, Biseptrin, Cotrimoxazol, Daiphen, Diseptyl, Ectaprim, Epitrim, Infectrin, Medibiot, Megaset, Neotrim, Primotren, Purbac, Regtin, Sinatrim, Sulfamethoxazol, Sulfamethoxazole, Sulfametoxazol, Sulfoprima, Sulphytrim, Trelibec, Trimaxazole, Trimethoprim, Trimezol, Trimol, Trizole

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Also known as: Trimethoprim


Sulphatrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Sulphatrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Sulphatrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


This medication is given by injection into a vein as directed by your doctor. It is given by slow infusion over 60 to 90 minutes. Dosage is based on your medical condition, weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.


If you overdose Generic Sulphatrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Sulphatrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sulphatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Sulphatrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Sulphatrim is contraindicated in pediatric patients less than 2 months of age. Sulphatrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Characterizing the emission of chlorinated/brominated dibenzo-p-dioxins and furans from low-temperature thermal processing of waste printed circuit board. Characterization of these positively selected genes using Non redundant (nr) annotation, gene ontology (GO) classification, GO term enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that these genes are mostly involved in thylakoids, photosynthesis and metabolism. The prevalence of urinary incontinence in pregnancy among a multi-ethnic population resident in Norway. Imported shigellosis: aerogenic Shigella boydii 74 (Sachs A 12) in a traveller followed by two cases of laboratory-associated infections. Relationship between central corneal thickness and changes of optic nerve head topography and blood flow after intraocular pressure reduction in open-angle glaucoma and ocular hypertension.

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Our findings suggest that an early alteration of platelet sensitivity might play a key role in maintaining the hemostatic balance and could be of greater importance than the vascular wall PGI2-synthesis, as the sensitivity changes immediately, whereas the PGI2-formation change is a long-term process. Determination of paralytic shellfish toxins in shellfish by receptor binding assay: collaborative study. A lateral radiograph of the cervical spine with a focal-film distance of 6 ft was obtained of each subject to measure the sagittal diameter of the cervical spinal canal. The fact that the ability of glyco-gag to enhance XMRV infection varies in different cell lines suggests a glyco-gag sensitive restrictive factor that further reduces XMRV infectivity. DNA methylation landscapes: provocative insights from epigenomics. The prolonged residence of some gadolinium-chelates in the uremic milieu may allow free toxic gadolinium released from its chelate to extravasate into the extravascular space where it may accelerate fibrillogenesis.

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A total of 276 men with prostate specific antigen greater than 4 ng/ml (208) or a prostate specific antigen velocity change of 0.75 ng/ml (68) and a normal digital rectal examination who had previously undergone biopsy a minimum of 2 times with prostate cancer not detected were given 5 mg finasteride (154) or dutasteride (122) daily. Magnetic resonance imaging (MRI) of the brain revealed an abnormal development of the cerebral cortex in the left temporal lobe, which showed a simplified gyral pattern, and increased cortical thickness. Although screening programs have existed for a few decades, there are still many unsolved problems, such as how age or hormone affects the screening sensitivity, the sojourn time in the preclinical state, and the transition probability from disease-free state to the preclinical state. Other actions by aspirin may lead to small improvements of some symptoms (for example, lessening fatigue). A routine echocardiogram should be performed in all infants with syndromic HD to exclude cardiac abnormalities. Pregnant women are susceptible to vaginal colonization and infection by yeast.

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Recent Advances: Topical silicone gel treatments seem to remain the first point of clinical recommendation in scar management. Currently, surgical resection is one of only a few options for treating brain cancer. The voltage dependence of the chloride conductance of frog muscle. The verification results showed that the proposed method can be used to create a verifiable and predictable discriminant function by training data selection. Tissue heterogeneity is an argument against using TMAs, which has been dealt with by increasing the size and number of cores punched from each tumor. Exercise training improves PF and exercise capacity in children recovering from burns, yet it is unknown if adults will demonstrate the same response. Liver, kidney and lung of rabbits with the highest As concentrations at 16 and 48 hours showed a rapid clearance of As in the first 48 hours. As part of the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER), we aimed to determine if there are differences in serum concentrations of pediatric biochemical markers measured at fasting, postprandial, and random time points throughout the day.

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Immunogenetic predisposition to chronic nonspecific inflammatory bowel disease. Like ketamine and other arylcyclohexylamine compounds, methoxetamine is thought to be both a noncompetitive NMDA receptor antagonist and a dopamine reuptake inhibitor. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) are less invasive than bone marrow mesenchymal stem cells to obtain for cell therapy. One powerful statistical model uses a Fourier approach to model cardiovascular signals as a harmonic sum of sinusoids with a fundamental frequency, amplitudes, and phases that vary slowly over time. High-dose medroxyprogesterone acetate in advanced male breast cancer. Metastases of pancreatic adenocarcinoma: A systematic review of literature and a new functional concept. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2011, Issue 9), MEDLINE (January 1950 to September 2011), EMBASE (January 1980 to September 2011), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to September 2011), the metaRegister of Controlled Trials (mRCT) ( and ( This operative procedure is the method of choice for pseudoarthrosis of the neck of the femur without evidence of avascular necrosis of the femoral head.

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Changes in the bone-cement interface after total hip replacement. The semiology of eight dysspondylies in individual segments of the spine is described. Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge. There is no doubt that industry must support the idea of putting patients first, but procedural considerations in fixing causality and determining the quantum of compensation promise to raise questions of morality, ethics, and jurisprudence that can i drink alcohol taking cymbalta will not be easy to answer. The method provides a useful pathway of scaffold preparation and cell transplantation, which can achieve suitable mechanical properties and good cell performance simultaneously. New targets including the collagen receptor, glycoprotein VI (GPVI), and the GPIb-von Willebrand factor axis, governing platelet interaction with the diseased vessel wall, should enable us to complete the armamentarium of antiplatelet drugs.

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To date, drugs prescribed for treatment of these diseases target enzymes that are not specific to the immune system resulting in adverse effects. Evaluation of the titanium dioxide approach for MS analysis of phosphopeptides. Defect in assimilation following combined radiation and chemotherapy in patients with locally unresectable pancreatic carcinoma. Seroepidemiological study of human hydatidosis in meshkinshahr district, ardabil province, iran. Here, we investigated the ability of resveratrol, a component of red wine, to prevent peroxynitrite-mediated endothelial cells toxicity and the underlying mechanism. Veterans aged 70 or older without a prior diagnosis of cognitive impairment. Tar-induced skin lesions are still of importance nowadays, which is reflected in the incidence of new cases and in the relapses of skin tumors. Editorial overview: Immunomodulation: New insights for future treatments. The mucin fraction was isolated by precipitation with Cetavlon, and characterized in terms of amino acid and carbohydrate composition.

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Central nervous system and biogenic monoamines: study on the locus coeruleus in cats. Only FreeStyle 293-F cells showed significant Dkk1 protein expression in culture medium. The HFB method does not require explicit knowledge of the free energy to locate the path. The aim of our study was to evaluate changes in BM-MSC and PLSC caused by ionizing radiation. Nocturia, sleep-disordered breathing, and cardiovascular morbidity in a community-based cohort. Towards a movement quantification system capable of automatic evaluation of upper limb motor function after neurological injury. Therefore, we next analyzed the orthotopic tumor growth of PAN02 cells transduced with MMP9 or a control empty vector. A heating stage enables measurement of the residual stress as a function of temperature. Calculation of carbon-13 nuclear magnetic resonance relaxation times and nuclear Overhauser enhancements and comparison with experiment.

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