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Sigmet (Metoclopramide)

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Sigmet antagonizes the effect of dopamine in the central nervous system and other organ systems. Sigmet's effect on the medullary chemoreceptor trigger zone makes it useful as a routine anti-emetic and in preventing vomiting induced by antineoplastic drugs, particularly cisplatin.

Other names for this medication:
Acimet, Actinorm, Cepar, Cerinorm, Clomet, Copar, Cosmet, Donmet, Elinorm, Emenil, Maxeron, Maxinorm, Megatech, Metadrate, Metanorm, Metcon, Metochlopramide, Metocin, Metoclopramide, Metocontin, Metomit, Metopar, Metozolv, Metvo, Migrosh, Molmet, Naushi, Norvin, Nutec, Pacimol, Paramet, Paranorm, Perinorm, Peripan, Peronorm, Promet, Propamid, Pymet, Regurg, Rivnorm, Vagonorm, Vominil, Vominorm, Vomitex, Vomitrac, Vomitran, Vomonil, Zerinorm

Similar Products:
Avodart, Mellaril, Ceftin, Nimotop, Prevacid, Provigil

Also known as: Metoclopramide


Sigmet is an anti-viral drug indicated for severe RSV infection, hepatitis C infection and other viral infections. Sigmet is manufactured by Merck Sharp and Dome (a subsidary of Merck and Co., Inc.). The active ingredient, Ribavirin is a professional grade drug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for replicationSigmet. Ribavirin helps the immune system fight the virus and makes it harder for the virus to reproduce within the body. Sigmet is prescribed in combination with other medications such as sofusbuvir and peginterferon alfa 2a/2b for preventing hepatitis C virus (HCV) cells from multiplying in your body. Treatment of HCV genotypes 1, 2, 3 and 4 is possible with Sigmet, however it is never used on its own.


Some brands of Generic Sigmet may be taken with food. Others should be taken on an empty stomach. Some brands of Generic Sigmet must be swallowed whole. Take Generic Sigmet by mouth with or without food. Take Generic Sigmet with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Generic Sigmet. If you also take bismuth salts (bismuth subsalicylate), calcium salts (calcium carbonate), colestipol, iron salts (iron sulfate), magnesium, urinary alkalinizers (daily antacids), sucralfate, vitamins/minerals, quinapril, didanosine, or zinc salts (zinc sulfate), do not take them within 2 to 3 hours before or after taking Generic Sigmet. To clear up your infection completely, take Generic Sigmet for the full course of treatment. Keep taking it even if you feel better in a few days. Generic Sigmet works best if it is taken at the same time each day. If you want to achieve most effective results do not stop taking Generic Sigmet suddenly.


If you overdose Sigmet and you don't feel good you should visit your doctor or health care provider immediately.


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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Sigmet if you are allergic to Generic Sigmet components. Do not take Generic Sigmet if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Generic Sigmet if you are taking sodium oxybate (GHB). Do not take Generic Sigmet if you have kidney disease. Generic Sigmet should not be given for more than 3 days in a row except for the treatment of tetanus. Use Generic Sigmet with caution in the elderly people. They may be more sensitive to its effects. Generic Sigmet should be used with extreme caution in children younger than 12 years old. Safety and effectiveness in these children have not been confirmed. Avoid alcohol. Avoid machine driving. Do not stop take it suddenly.

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