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Qubol (Anastrozole)

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Qubol lowers estrogen levels in the body, particularly the form of estrogen known as estradiol. Many breast tumors display estrogen receptors on cell surfaces. When these receptors are bound to estrogen it is thought that cell growth and thus tumor growth are stimulated.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Luvox, Duricef, Mobic, Thorazine, Pamelor, Famvir, Sumycin, Seroquel, Aldactone, Rocaltrol

Also known as: Anastrozole


Qubol is approved to treat certain types of breast cancer in women who’ve gone through menopause.

What breast cancer is

Breast cancer develops when cells in your breast start to grow and multiply (make more cells) more quickly than usual. With most breast cancers, the abnormal cells are encouraged to grow by the hormone estrogen.

If your breast cancer is stimulated by hormones, such as estrogen, certain tests will show that the cancer cells have receptors (attachment sites) for those hormones. This type of breast cancer is called hormone receptor-positive (HR+).

HR+ cancers can be treated with hormone therapies that lower the estrogen level in your body. And because most breast cancer is HR+, hormone therapies are also sometimes used to treat breast cancer whose receptor status isn’t known.

What Qubol does

Qubol is a hormone therapy that’s used to treat certain forms of breast cancer. It’s a type of drug called an aromatase inhibitor. Qubol works by stopping (inhibiting) the action of an enzyme called aromatase. (Enzymes are certain proteins that help chemical reactions to happen inside your body.)

The aromatase enzyme makes estrogen out of steroid hormones in your body, such as testosterone. Aromatase is found in various tissues, including your brain, fat, and skin.

Before menopause, estrogen is mainly produced by your ovaries. And just a small amount is made by the aromatase enzyme. But after menopause, your ovaries stop producing estrogen. At that point, the aromatase enzyme is the main way that your body makes estrogen. (And in men, estrogen is also mainly produced by the aromatase enzyme.)

By stopping aromatase from working, Qubol lowers the amount of estrogen in your body. This helps to stop estrogen from encouraging breast cancer to grow and spread.

How long does it take to work?

Qubol will start working soon after you begin taking it. But you won’t be able to notice this. Your doctor may order different kinds of tests during your treatment to check and see if the drug is working for you.


This medicine may be taken on an empty stomach or with food. Take this by mouth exactly as directed usually once a day. This is a potent medication. Do not increase your dose, or take this more often than directed. If you want to achieve most effective results do not stop taking Generic Qubol suddenly.


If you overdose Generic Qubol and you don't feel good you should visit your doctor or health care provider immediately.


Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Qubol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Qubol can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Qubol and other medications

Below are lists of medications that can interact with Qubol. These lists do not contain all the drugs that may interact with Qubol.

Before taking Qubol, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Qubol and tamoxifen

Like Qubol, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Qubol can lower the amount of Qubol in your body. This can make Qubol less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Qubol. However, if recommended by your doctor, it’s fine to take Qubol after you’ve finished taking tamoxifen.

Qubol and drugs that contain estrogen

Taking Qubol with drugs that contain estrogen could make Qubol less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Qubol.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Qubol, talk with your doctor.

Qubol and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Qubol. However, you should still check with your doctor or pharmacist before using any of these products while taking Qubol.

For example, it’s possible that supplements such as red clover or wild yam could make Qubol less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Qubol.

Qubol and foods

There aren’t any foods that are known to interact with Qubol. Talk with your doctor to find out if there are any foods you should avoid during Qubol treatment.

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The future of ozone therapy must focus on the establishment of safe and well-defined parameters in accordance with randomized, controlled trials to determine the precise indications and guidelines in order to treat various medical and dental pathologies. The content of cholesterol in the diet of men was higher than recommended. An unexpected benefit may be to drive more collaborative learning. They decreased the net photosynthetic rate (Pn), photochemical efficiency (Fv/Fm), and actual photochemical efficiency (PhiPSII) significantly, but their action mechanisms were differed. Networking between community health programs: a case study outlining the effectiveness, barriers and enablers. The purpose of this work was to describe illnesses and injuries sustained by campers at summer camps, calculate illness and injury rates, and identify risk factors for camp-related illness and injury. In Greek mythology twins caused ambivalent reactions and were believed to have ambivalent feelings for each other. Only naloxone (10 mg/kg) affected spontaneous activity in rats tested individually, decreasing both gross and fine activity. The significance of the presence of anti-IgA antibodies in individuals with an IgA deficiency. In vitro comparison of the maxillary occlusal plane orientation obtained with five facebow systems.

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We provide evidence that the neural cell adhesion molecule (NCAM)-derived mimetic peptide, FG loop (FGL), acts as a novel anti-inflammatory agent. Pharmacological or RNA interference-mediated inhibition of ceramide biosynthesis enhanced apoptosis and impaired primitive ectoderm formation in embryoid bodies differentiated from mouse embryonic stem cells. The aim of this study was to describe the development of a Nurse Cultural Competence Scale using Mokken scaling. Influence of serum inactivation on the detection of rheumatoid factor in patients with possible or probable rheumatoid disease. The aim of this study was to characterize the root extract of the medicinal plant Coleus forskohlii.

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Human CYP1A1 followed by 3A4 had the highest intrinsic clearance (CLint) for DEA formation whereas in rat, CYP2D1 followed by CYP2C11 had the highest CLint. More variable results are reported in secondary dystonias and its efficacy in this heterogeneous group has not been fully elucidated. Personalized medicine, which is based on pharmacogenetics, holds great promise in solving these types of problems. We hypothesized that alterations in connexin43 expression and localization in the mouse heart might be induced by ventricular pacing over a short period of time. Traditionally, benefit-cost (B-C) models have been limited to the consideration of monetary benefits. A preliminary study on free medial sural artery perforator flap for head and neck reconstruction following tumor ablation. Penicillin toxicity in isolated rat hepatocytes revealed by decreased incorporation of valine into proteins. The Bramwell-Hill model describes the relation between vascular wall stiffness expressed in aortic distensibility and the pulse wave velocity (PWV), which is the propagation speed of the systolic pressure wave through the aorta. The findings also suggest that strong reservations have to be made regarding the validity of a SR test, as predictor of VO(2peak) in a wheelchair user population.

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Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin. Preoperative and postoperative IIEF and EDITS scores were compared as were the patients who complained of penile length loss with those who did not. Clinical considerations, therapeutic indications and results in 8 cases of ocular torticollis. Neither diol-epoxide was significantly, if at all, metabolized by epoxide hydrolase. Krypton Adsorption on Zeolite-Templated Carbon and Anomalous Surface Thermodynamics. Toxicity of prilocaine and bupivacaine in intravenous regional anesthesia. In vitro cultures of human PSCs were exposed to curcumin and L49H37. The CFA profiles for the infants fluctuated from hour to hour during the first days of life and resembled those for both the mothers and the nurses, doing so all the more in the case of the five infants examined 6 months after birth. To determine the prevalence of antimicrobial resistance in clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis from medical centres across Canada.

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Obesity has emerged as one of the leading medical challenges of the 21st century. Biotransformations of medicinal and toxic substances: importance of their study in general biology, in therapeutics and in industrial hygiene. The ability to differentiate between two stimuli is based on the physiological mechanisms of hearing. A high degree of suspicion should be maintained and patients must be monitored even during the recovery phase of dengue fever. To report a case of fatal alveolar hemorrhage associated with the use of everolimus in a patient who underwent a solid organ transplant. On smoke and soot contamination of the city of Bebra by railway machinery.

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Retrieving and comparing biometric data from the files of 163 consecutive patients seeking cataract extraction by PCI (IOLMaster) and US (Sonomed). Integrating conventional science and aboriginal perspectives on diabetes using fuzzy cognitive maps. AMPA receptor potentiation activates multiple intracellular neurochemical cascades and the present report identifies BDNF as one key mediator of the neurotrophic effects of AMPA receptor potentiation. We conclude that dietary changes can have a profound influence on prostaglandin and thromboxane synthesis of organ systems. The ATSM is a robust method and able to provide accurate C(rs) in spontaneously breathing patients during pressure support ventilation noninvasively without extra instrumentation or complicated maneuvers.

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To assess the lead exposure of children, to propose control measures and evaluate the impact of these measures. Feed intake, rumen fermentation and milk production in milking cows. The concentrations of total selenium and total mercury in the muscle of striped mullet from four stations in the Northern Tyrrhenian Sea and one in the Black Sea were analyzed. Baseline information, obtained through a questionnaire, together with history at first consultation, provided information for referral, demographic and presentation profiles. Adenoid cystic breast carcinoma: a salivary gland-type tumour with excellent prognosis and implications for management.

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Crosstalk Between Bioactive Peptide and Intestinal Barrier in Gut Homeostasis. Age-related decrease in prostacyclin biosynthesis is also found when protaglandin H2 is used as substrate. Blood-aqueous barrier breakdown was quantified by use of anterior chamber fluorophotometry, with fluorescein entry into the anterior chamber measured 2 and 9 days after surgery compared with baseline scans obtained prior to surgery. Postnatal development of adipose tissue in normal children on strictly controlled calorie intake. Applying microRNAs for treatment of brain tumours poses several problems, and fields to be solved are mainly the passage of the brain-blood barrier and the targeted delivery to specific cell types. Even though there is no consensus for a standardized or evidence-based therapy in literature, this article gives an overview of the diagnostics and available therapeutic options.

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Based on the trnT-F cpDNA region, PCR assays were developed to identify two plant families (Poaceae and Apiaceae), the genera Trifolium and Plantago, and nine plant species: Achillea millefolium, Fagopyrum esculentum, Lolium perenne, Lupinus angustifolius, Phaseolus coccineus, Sinapis alba, Taraxacum officinale, Triticum aestivum, and Zea mays. Lactic fermentation of cellobiose by a yeast strain displaying beta-glucosidase on the cell surface. It was found that the average color difference between the complex scenes correlates well with the color differences of the Munsell samples with an average correlation of about 0.94, a result indicating that the Munsell set can be used to predict chromatic changes in complex scenes. Polymorphonuclear leukocytes (PMN) and monocytes from the patient show a normal phagocytosis, whereas the oxygen metabolism and the intracellular killing of kastalase-positive microorganismus (Staphylococcus aureus, Candida albicans) are strikingly decreased. To analyse whether sufficient scientific evidence exists to recommend preoperative weight loss in candidate patients for bariatric surgery.

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