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Nuvigil (Armodafinil)
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Nuvigil

Nuvigil is a medication that promotes wakefulness. Nuvigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Nuvigil may also be used for purposes not listed in this medication guide.

Other names for this medication:
Armod, Armodafinil, Biryth, Waklert

Similar Products:
Leukeran, Compazine, Microzide, Retin, Trandate, Silagra, Eulexin, Zanaflex

Also known as: Armodafinil

Description

Nuvigil is a prescription medication used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: narcolepsy, obstructive sleep apnea (OSA), shift work disorder (SWD).

Nuvigil is used with other medical treatments for this sleep disorder. Nuvigil does not take the place of using your CPAP machine or other treatments that your doctor has prescribed for this condition. It is important that you continue to use these treatments as prescribed by your doctor.

Nuvigil is in a class of medications called wakefulness-promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.

Dosage

Take Nuvigil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Armodafinil may be habit-forming. Never share Nuvigil with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Nuvigil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.

You may take this medicine with or without food. Nuvigil is usually given for up to 12 weeks. Follow your doctor's instructions.

If you are taking this medicine to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction. Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Nuvigil may be necessary to best treat your condition.

Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking this medicine. Nuvigil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.

Overdose

When a person takes too much Nuvigil, overdose symptoms may include unusual bruising or bleeding, nausea, diarrhea, and chest pain. Specific effects will be based on certain factors. If the Nuvigil overdose was recent, healthcare providers may give certain medicines, place a tube in the stomach to pump the stomach, or treat the symptoms that occur as a result of the overdose.

Storage

Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Nuvigil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Nuvigil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking Nuvigil, tell your doctor or pharmacist if you are allergic to it; or to modafinil; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as enlarged heart, mitral valve problem, chest pain, heart attack, irregular heartbeat), heart problems after taking stimulant drugs such as amphetamines (including chest pain, irregular heartbeat), high blood pressure, liver problems, mental/mood disorders (such as depression, mania, psychosis), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol).

Sleep disorders may reduce your ability to react quickly. Though Nuvigil helps keep you awake, you still may not be able to safely do things that require quick reactions (such as driving). This drug may also make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

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Individual differences in responses to provocation and frequent victimization by peers. Several sperm surface proteins are associated with their migration through the cervical mucus and the UTJ. In this issue of Neuron, Tessier-Lavigne and colleagues demonstrate that two different spliced isoforms of the Robo3 receptor act sequentially in commissural neuron growth cones to mediate this process at the ventral midline in the vertebrate spinal cord. The pseudotumor was probably the result of inflammatory reaction in both tubes and in the uterine cavity, with pyometra. Aortic valve replacement: choice between mechanical valves and bioprostheses. Ino2p and Ino4p bind to Apl2p in the same region of Apl2p, viz., at the middle part and the C-terminal part.

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The surface of the epithelium at a location corresponding to the planum semilunatum in the adult organ has a thick layer of microvilli and demonstrates a particularly high secretory activity on the 15th gestational day. Two cases of successful surgical management of aneurysm of the splenic artery are presented. Med1/TRAP220 is an essential component of the TRAP/Mediator complex. In addition, the proposed modes of inhibition of peptide inhibitors are also discussed. The reasons for this nitric oxide deficiency are incompletely understood but may include reduced production from nitric oxide synthases due to decreased expression, the enzymes in airway epithelial cells, reduced availability of L-arginine, the substrate for nitric oxide synthases, and the presence of endogenous inhibitors of the enzymes in the airways. These patterns open new insights on the role of 18F-NaF in the study of calcification and in the identification of the vulnerable carotid atheroma. Patients with orbital, medial and right lateral damage confabulated in response to questions probing orientation to time (OT).

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The revealed differences in biocenoses dynamics of 2 biotopes of upper respiratory tract in healthy individuals, bacteria carriers and individuals after tonsillitis may be used to forecast stable health and development of dysbiotic disorders. These different behaviors are also reflected in the average particle dynamics, quantified by the mean squared displacement of the individual particles, and the fraction of active regions. Brucella strains containing the O-polysaccharide in their cell wall trileptal maximum daily dose structure exhibit a smooth phenotype whereas the strains devoid of the polysaccharide show rough phenotype. A technique for rapid diagnosis of astroglial and ependymal glial neoplasms is presented. Coordinated Action of Aquaporins Regulates Sperm Motility in a Marine Teleost.

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In the in-plane technique, the needle was advanced through the respective segmental intertransverse ligament. Wolffian ducts (WDs) are the embryonic structures that form the male internal genitalia. Influence of host tree condition on the performance of Tetropium fuscum (Coleoptera: Cerambycidae). Silymins A ( diflucan drug coupon 1) and B (2), the new pentacyclic triterpenes, have been isolated from ethyl acetate fraction of Silybum marianum and their structures assigned from 1H and 13C NMR spectra, DEPT and by 2D COSY, NOE and HMBC experiments. Adverse events are mostly mild and transient and occur at the same rate as with placebo. In both cases the small perturbation of the Raman spectrum of hydrogen indicates that adsorption takes place without any evident charge transfer between H(2) and the adsorbent. Moreover, the emphasis has been laid on the application of modern medical knowledge and technology to traditional acupuncture-moxibustion in order to explore the mechanism of acupuncture analgesia and to determine the effectiveness of acupuncture-moxibustion in the treatment of diseases.

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Significant CMAP decrement by repetitive nerve stimulation is more frequent in median than ulnar nerves of patients with amyotrophic lateral sclerosis. Cellular ingestion, toxic effects, and lesions observed in human bronchial epithelial tissue and cells cultured with asbestos and glass fibers. Safety and complications of percutaneous kidney biopsies in 715 children and 8573 adults in Norway 1988-2010. Comparison of ELISA and RIA for measurement of pneumococcal antibodies before and after vaccination with 14-valent pneumococcal capsular polysaccharide vaccine. The effect of nitrogen intake upon the urinary riboflavin excretion of young male adults. Obstacles to the achievement of SLM are discussed and the steps necessary to overcome them are presented.

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Lentivirus containing specific sequences of hTERT gene could significantly inhibit the growth of nasopharyngeal carcinoma cells line. PI-LZerD consistently showed better prediction accuracy over alternative methods in the series of benchmark experiments including docking using actual docking interface site predictions as well as unbound docking cases. Lawsone (2-OH-1,4-naphthoquinone) derived form the henna plant increases the oxygen affinity of sickle cell blood. However, an increased number of estimated ovulatory cycles correlates directly albenza tablet with risk for both endometrial and ovarian cancer, suggesting that reproductive tissue turnover with an accumulation of PTEN or p53 mutations represents a possible common mechanism. The impact of critical time intervention in reducing psychiatric rehospitalization after hospital discharge. Nox4 overexpression induced basal activation of ERK1/2 and JNK whereas Nox2-transfected cells showed a modest increase in p38MAPK activation. Combined with the known ratio of phenylalanine to tyrosine in rapidly growing E. Engineered and Native Coenzyme B12-dependent Isovaleryl-CoA/Pivalyl-CoA Mutase.

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Response to public concern about potential adverse environmental and health impacts has led to the formation of state and national advisory committees. Functional magnetic resonance imaging (fMRI) is based on correlating blood oxygen-level dependent (BOLD) signal fluctuations in the brain with other time-varying signals. However, the bacteria were not successfully eradicated with 2- or 12-week ingestion of a Bainiku-ekisu solution. Internalization of the pathogen results in the formation of a phagosome that is supposed to fuse with lysosomes to form phagolysosomes, which serve the degradation of the pathogen, an event actively prevented by some pathogens. The compounds involved were classified by chemical and therapeutic class. We implemented this approach in conjunction with 2D Traction Force Microscopy to compare cytoskeletally-mediated forces of cells in 3D collagen matrices to forces exerted by cells on 2D collagen-coated hydrogel substrates.

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The present results suggest that miR-155 expression is decreased in active BD but not in VKH patients. Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. The results presented here may explain attraction of adult moths to sweet baits as well as to odors from ripe fruit, which may be a natural source of food in the fall. The results confirm the presence of seasonal variations in episodes of idiopathic PE and an association between decreased atmospheric pressure and increased temperature. Linear regression analysis showed that HMGB1 and MyD88 positively correlated with CTSB among the whole healthy people. dP/dt(max) is the maximal rate of rise of (usually) left ventricular pressure (LVP), but it is determined by myocardial contractility and the loading conditions on the ventricle, thus it is an imperfect and sometimes incorrect predictor of the inotropic state (myocardial flomax cost without insurance contractility).

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