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Metrin (Metronidazole)
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Metrin

Metrin is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Acuzole, Anegyn, Biozyl, Birodogyl, Farnat, Flagemed, Florazole, Medazol, Menizol, Metral, Metrobac, Metrol, Metrolag, Metronidazolum, Metronide, Metronour, Metrozin, Metrozine, Metrozol, Monizole, Nizole, Promuba, Repligen, Rosasol, Tismazol, Tolbin, Tricodazol, Unigyl, Vandazole, Varizil

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Also known as: Metronidazole

Description

Metrin (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metrin is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Metrin 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Metrin and 250 on the other side; bottles of 50, 100, and 2,500. Metrin 500-mg tablets are oblong, blue, film coated, with Metrin debossed on one side and 500 on the other side; bottles of 50, 100, and 500.

Overdose

Single oral doses of Metrin, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Metrin has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Metrin overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store Metrin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Metrin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Metrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Metrin Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Metrin Tablets is contraindicated during the first trimester of pregnancy.

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Mother milk and the Indonesian economy: a major national resource. Therefore, despite their impairment in reading acquisition, developmental dyslexics have the ability to encode and exploit letter frequency co-occurrences. Gist Representations and Communication of Risks about HIV-AIDS: A Fuzzy-Trace Theory Approach. Value of the innovated technique agarose cell block in improving the sensitivity of urine cytology in cases of bladder carcinoma. After TCDD treatment, the mRNA levels of antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase) were significantly decreased.

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In the presence of dopamine-neuron target cells from the corpus striatum, a dense axonal plexus characteristic of that formed in this area in vivo was observed. FSL J1-208, a virulent uncommon phylogenetic lineage IV Listeria monocytogenes strain with a small chromosome size and a putative virulence plasmid carrying internalin-like genes. The regulation of the penicillin acylase in proteus rettgeri ATCC 31052 was compared with that of the enzyme in Escherichia coli ATCC 9637. Bacterial endophthalmitis following cutting of sutures after cataract surgery. We propose that a novel naphthochalcone derivative TDPN is capable of promoting keratinocyte migration via the induction of EMT resulting acceleration of wound closure and matrix remodeling. Parallel immunohistochemical analysis of the RB pathway was conducted on pretreatment biopsies to determine the association with pathologic response to neoadjuvant chemotherapy.

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Staphylococcus aureus ATCC 29213 and 25923, Streptococcus pneumoniae ATCC 49619, and Haemophilus influenzae ATCC 4927 strains were evaluated. Controlled clinical experiment with the topical use of 2-(3-benzoyl-phenyl) propionic acid at 3 different concentrations. Attitudes of medical school deans toward interprofessional education in Western Pacific Region countries. Path analysis was utilized to explore the relationships of community and family economic and cultural contexts with child culture brokering, child emotional distress, and family disagreements. Despite a certain heterogeneity among the various studies, the use of ANuA appears more efficacious than anti-dsDNA. Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat. Routine Outcome Monitoring ROM is an important instrument for measuring the effectiveness of treatment and has been implemented in the Dutch mental health care system.

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Quest for Orthologs Entails Quest for Tree of Life: In Search of the Gene Stream. Unfortunately, the complexity of the free radical-mediated processes that are perturbed in complex pathologies such as DMD will make it difficult to develop therapeutic approaches founded on systemic administration of antioxidants. Relaxation of accommodation proceeded at a fairly constant rate upon cessation of electrical stimulation. Chest pain presentations are common although most patients do not have an acute coronary syndrome (ACS). Effect of melatonin on proliferation and apoptosis of fibroblasts in human hypertrophic scar. In this paper, a method based on symbolic dynamics for the detection of time-delayed coupling in biosignals is presented. Comparison of localized versus systemic levels of Matrix metalloproteinases (MMPs), its tissue inhibitors (TIMPs) and cytokines in tuberculous and non-tuberculous pleuritis patients.

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Intramedullary spinal schwannoma: case report and review of preoperative magnetic resonance imaging features. For example, tracking animal movement in 3D with simultaneous quantification of fluorescent transgenic reporters allows for correlations between behavior, aging and gene expression. The risk assessment was possible mainly because of factors such as early onset CRC, the presence of multiple primary tumours and a high risk family history. Bladder exstrophy patients, who undergo a successful primary closure, can achieve satisfactory capacities despite smaller bladder templates at birth. Uptake and release of 3H-mitomycin C in mouse P-388 cell cultures. A significant rise in plasma PTH was observed on day 7 and 14 after magnesium deficiency. It allows us to obtain a vibrational fingerprint of the adjustable molecular junction while performing electron transport measurements on the molecule simultaneously. Randomized, controlled, double-blind, phase 1 trial of a gel containing 3 different concentrations of TMC120 versus placebo.

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Less is more: the influence of traffic count on drinking and driving behaviour. There is a current demand to investigate this topic, because of retention of staff and a shortage of qualified nurses. To successfully derive endothelial cells from porcine iPSCs and demonstrate their potential utility for the treatment of myocardial ischemia. The relationship between perfectionism, eating disorders and athletes: a review. The SP were characterized using elemental analysis and infrared and (29)Si NMR spectroscopies, while their chromatographic behaviors were investigated by separation of selected neutral, acidic and basic compounds of different test mixtures (Engelhardt, SRM 870 and Tanaka tests). AR in VSD come from a deficiency or hypoplasia of the conal septum which leads to abnormal apposition in diastole and prolapse of the poorly supported noncoronary or right coronary cusp through the VSD into the right ventricle resembling subpulmonic stenosis and subsequently results in distortion of the aortic valve and progressive AR. The medical problems of chronic uraemia and chronic intermittent haemodialysis in children are discussed. On the day following the last administration, the animals were sacrificed and the distal colon was isolated, weighed, macroscopically examined, and processed for histology. Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia.

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The role of psychiatric illness in the association between the PSQI and a prospective, sleep diary-derived sleep quality measure (SDSQ) was investigated plus the degree to which the PSQI may reflect mood states. Artificial Intelligence for Pathologists Is Not Near--It Is Here: Description of a Prototype That Can Transform How We Practice Pathology Tomorrow. Characteristics of fibrin formation and clot stability in individuals with congenital type IIb protein C deficiency. Severe gastric dilation can occur with Rett Syndrome and may cause gastric necrosis and perforation. Polymerase chain reaction amplification, single-strand conformational polymorphism analysis and restriction endonuclease analysis were employed to identify and determine the frequencies of FECH sequence variations, including the IVS3-48C polymorphism, in a study cohort of symptomatic and asymptomatic South African EPP family members, and a matched control cohort. Adjuvant therapy consisted of 4 cycles of paclitaxel (175 mg/m(2)) and carboplatin (350 mg/m(2)) every 3 weeks, followed sequentially by external beam radiotherapy (RT) to the pelvis (45 Gy), followed by an additional two cycles of chemotherapy. This review begins with a review of the very earliest GPCR structural information, mostly derived from rhodopsin. Ion chromatographic determination of hydrolysis products of hexafluorophosphate salts in aqueous solution. Following activation of the innate immune system, strong inflammatory signals are generated inducing inflammation and activation of the adaptive immune response. The results show that treatment with the MEK1/2 inhibitor U0126 in ischaemic stroke decreases brain damage, neurological symptoms, and ET receptor alteration.

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Recent biodiversity research has focused on ecosystem processes, but less is known about responses of populations of individual plant species to changing community diversity and implications of genetic variation within species. For subsequent mass spectrometric analysis stable-isotope-labeled internal standards were used. RAGE is one of the major receptor to induce apoptosis of macrophages, and the up-regulation of its expression is induced by HMGB1. Treatment with mood stabilizers increased an active form of Notch receptor and upregulated its target genes in neural stem/progenitor cells, whereas coculture with gamma-secretase inhibitor or the presence of mutation in the presenilin1 gene blocked the effects of mood stabilizers. In this review, we analyze the factors determining protein 3-nitrotyrosine formation, the functional and biological outcome associated with protein tyrosine nitration, and the fate of the nitrated proteins. No data have been reported so far on the long-term benefits and safety of new-generation drug-eluting stent in ST-segment elevation myocardial infarction according to diabetes. Both the model-prediction and experimental derivations were remarkably consistent with each other except at pH 2. This chapter presents some guidelines for working with a statistician, beginning with when and why you should consult one. We analyze a model statistical description of the polypeptide chain helix-coil transition, where we take into account the specificity of its primary sequence, as quantified by the phase space volume ratio of the number of all accessible states to the number corresponding to a helical conformation. The anti-biofilm activity of the agents was assessed on biofilms grown under static (on microplates) and dynamic (in a CDC-reactor) flow regimes.

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Potentiation of solid-tumor chemotherapy by metabolic alteration. Yet, breast and ovarian cancer screening for all women who are on long term drugs that induce weight gain or hyperprolactinemia should not be neglected. Formal assessment to understand the extent, possible causes and implications was undertaken. There is relationship between EFI and pregnancy in patients with endometriosis-associated infertility. The operator-computer interaction is colloquial through the use of a priligy tablets video-terminal, permitting the use by nominally-trained staff. Conversely, silencing of S100P in 22Rv1 cells using siRNA resulted in a prominent cytostatic effect. Hearing preservation rate after retrosigmoid craniotomy for intracanalicular vestibular schwannomas may be superior for tumors with fundal extension compared with tumors that do not extend to the fundus.

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By means of appropriate model systems, the methodology has been developed and successfully validated. To calculate the dihedral angles casodex chemotherapy cost distribution functions, the configuration space was divided into cells by a cubic grid. Hematoporphyrin derivative as a tumor marker in the detection and localization of pulmonary malignancy. However, Dalla Valle used different formulae for slot and plain opening (rectangular) hoods, and the calculated values near the boundary between the slot and plain opening by these formulae do not always match each other. The CbrA regulator in Pseudomonas represents a unique type of sensor kinase whose autokinase domain is connected to a transporter domain. The aim here was to investigate insulin stimulation of the Akt/PKB pathway in the placenta, in normal and preeclampsia parturients. MetRxn: a knowledgebase of metabolites and reactions spanning metabolic models and databases.

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However, the synthetic methodologies and potential applications of these novel and interesting materials have not been reviewed comprehensively in the literature. Guideline developers should specify the relative importance of the outcomes before gathering the evidence and again when evidence summaries are complete. Antitumor activities were tested in mice with experimental tumor H22 in vivo, and the thymus index, spleen index and tumor inhibitory rate were evaluated. Implications of the accuracy of MEPS prescription drug data for health services research. The article summarized the latest progress of retinoblastoma animal models using transgenetic engineering technology, and discussed the mechanism of Rb production. Patients in the Stockholm region diagnosed with rectal cancer between January 2002 and December 2008, who received SRT (25 Gy over 5-7 days) and had surgery with resection of the primary tumour more than 4 weeks after the start of RT, were identified from a prospective register. This variation is not T cell controlled, but rather is releated to the relative number of monocytes in the system. The periprosthetic osteolysis model was made by injecting endotoxin-free pure polyethylene particles into the distal part of the femur canal and inserting a stainless steel plug into this femur. We describe a case of a 34-year-old woman with atrial fibrillation induced by focal frequent tachycardias from superior vena cava and atypical atrioventricular nodal reentrant tachycardia.

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