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Metpure (Metoprolol)

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Metpure is a selective beta blocker. It slows down the heart which allows it to put less pressure on the body's blood vessels. By slowing down the heart, it also allows the heart to use less oxygen which improves chest pain.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol


Metpure is a perfect remedy. Its target is to struggle against high blood pressure. It also can be used in the treatment of chest pain, heart attacks. Metpure acts by slowing the heart rate and relaxing the blood vessels. It is beta blocker. Metpure is also known as Toprol-XL, Metoprolol, Protomet, Lopresor, Lopresar. Generic name of Metpure is Metoprolol Tartrate. Brand names of Metpure are Toprol-XL, Metpure.


Take Metpure tablets orally with water. Take Metpure once or twice a day at the same time. Do not crush or chew it. If you want to achieve most effective results do not stop taking Metpure suddenly.


If you overdose Metpure and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Metpure overdosage: fainting, difficulty, breathing or swallowing, swelling of the hands, feet, ankles, or lower legs, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metpure are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Metpure if you are allergic to Metpure components. Do not take Metpure if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Metpure if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Metpure in case of taking cimetidine (Tagamet), clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem), hydroxychloroquine, paroxetine (Paxil), propafenone (Rythmol), quinidine (Quinaglute, Quinidex), ranitidine (Zantac), reserpine (Serpalan, Serpasil, Serpatab), ritonavir (Norvir), terbinafine (Lamisil),and thioridazine (Mellaril), bupropion (Wellbutrin). Be careful with Metpure if you have allergies to medicines, foods, or other substances. Be careful with Metpure if you suffer from or have a history of heart or liver disease; diabetes; severe allergies; or an overactive thyroid gland (hyperthyroidism), slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), had asthma or other lung disease. Use Metpure with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Avoid machine driving. Do not stop taking Metpure suddenly.

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The Prognostic Significance of c-MET and EGFR Overexpression in Resected Gastric Adenocarcinomas. Glutamate oxaloacetate transaminase (GOT) in the dy2J genotypes of C57BL/6J mice: possible involvement of regulatory defect in muscular dystrophy. Attention and memory biases toward body-related images among restrained eaters. There were no psychometric score differences between groups over the 3-month double-blind period. Impact of patient adherence to recommended medications on outcomes in populations with coronary artery disease.

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Block copolymers consisting exclusively of a silicon-oxygen backbone are synthesized by sequential anionic ring-opening polymerization of different cyclic siloxane monomers. In vitro activity of oral cephalosporins against pediatric isolates of Streptococcus pneumoniae non-susceptible to penicillin, amoxicillin or erythromycin. A retrospective analysis of the use of brachytherapy in relation to early stage squamous cell carcinoma of the oropharynx and its relationship to second primary respiratory and upper digestive tract cancers. It has been proposed that dysfunctional endothelial progenitor cells (EPCs) play a role in pathogenic vasculopathy in systemic sclerosis (SSc). The Si grains/interlayer formed at the interface and the presence of Si grains within the Er-related layer constitute proof that Si reacts with Er in the presence of a Pt top layer in the temperature range 450-600 degrees C. aureus bacteremia resulted in more-detailed evaluation, more-frequent detection of endocarditis and metastatic infection, and improved adherence to standards of care. As a result, formulas supplemented with DHA and ArA were introduced on the market. Current movements of four serious adverse events induced by medicinal drugs based on spontaneous reports in Japan.

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Specifically, 21-day-old rats had greater DAT levels compared to 45-day-old rats when in the NA, OT, and SN as well as in the OT compared to 75-day-old rats. Meanwhile, the bronchoscopic treatment of emphysema cannot yet be considered a standard of care and patients should be treated in the context of clinical trials or controlled registries, with well-defined programs of evaluation and follow-up. A minor CTL population recognizes alloantigens that are expressed by both EC and LC, but this population is necessary only for lysis of LC targets. This combination, plus a hard-wired culture of safety, has resulted in a dramatically lower mortality and harm rate that could not have been achieved with a partial solution. Research of the existing scientific literature and examination of multiple porcelain/metal samples indicate that Ni/Cr is not only compatible with veneering porcelain but, indeed, can probably be the basis for superior ceramo-metal restorations. High resolution T1-weighted, dual echo, and fluid-attenuated inversion recovery and diffusion tensor MRI images were prospectively acquired on 68 RRMS patients (range, 25-58 years) and 68 age-matched controls. More research on interventions and outcomes is particularly needed.

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Decreases in glomerular filtration rate and renal blood flow after insulin are thus due to the fall in blood glucose. The present study aims to evaluate the efficacy and toxicity of gefitinib readministration. We propose Syk inhibition as a potential therapeutic approach for the treatment of RA. Immunohistochemical localization of gastrin C-terminus, gastric inhibitory peptide (GIP) and endorphin in the pancreas of lizards with special reference to the hibernation period. Staged laparoscopic adjuvant IPCH after open or laparoscopic resection in selected patients with colorectal or gastric cancer is feasible and reasonably safe. The different profiles observed in the young adults were stable across ages with two exceptions: decreased lateral asymmetry for maximum grip force and increased asymmetry for sequential drawing in older individuals. Old and new environmental issues for college and university health services. Detection and quantification of bacterial autofluorescence at the single-cell level by a laboratory-built high-sensitivity flow cytometer. Pump to survive: novel cytoprotective strategies for cardiac progenitor cells. We searched databases including the Cochrane Menstrual Disorders and Subfertility Group (MDSG) Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PsycINFO and trial registers.

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The high-molecular-weight fraction was serologically active, and contained glucose as the only sugar. Thrombolysis for acute ischaemic stoke was introduced and licensed in Poland in 2003. There were about 150 attendees including students, postdoctoral fellows and prominent experts in different aspects of the field. Purification and identification of two distinct protein kinases. These include impaired mitotic mechanics, abnormal IGF2 expression, perturbed DNA-damage response, defective spliceosomal machinery, and abnormal replication licensing. The ultimate goal of cognitive remediation is to improve the functional outcome. The analysis shows the strengths of the associations of microinverter temperature with ambient temperature, PV module temperature, irradiance and AC power of the PV systems. VP seems to reduce the implant time and the need to implant on the other side as well as implant failure due to the inability to gain venous access. It is unknown whether JNK1 regulates glycolysis, an important metabolic process that is involved in cell survival, and if so, whether the regulation depends on Thr-201 phosphorylation of Bad. Combined spinal-epidural anesthesia for cesarean delivery in a patient with capillary pontine telangiectasia.

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Studies were searched using CINAHL, EMBASE, MEDLINE, PsycINFO, and PubMed databases. Retrospectively, it was established that the animal had had a periodic nasal discharge for many months. Any effort to make sense of the complexities of contemporary midwifery must deal not only with biomedical and governmental power structures but also with the definitions such structures impose upon midwives and the ramifications of these definitions within and across national and cultural borders. Evaluation of immunostimulatory and growth promoting effect of seed fractions of Achyranthes aspera in common carp Cyprinus carpio and identification of active constituents. Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion. Before, during and after you disappear: aspects of timing and dynamic updating of the real-time action simulation of human motions. We present emerging evidence suggesting that the membrane biophysical properties of oxysterols underlie their acute cholesterol-regulatory functions and discuss the relevance of these acute effects to cholesterol overload in physiological and pathophysiological states.

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Angiotensin II, Calcitonin gene related peptide and histamine had minimal effect on post pressure blood flow. The evidence obtained may be of use in the devising of a method for differential diagnosis of tumors of different genesis. Recent case reports suggest that splenic rupture occurs in people without known risk factors for severe babesiosis. Interrater reliability of cardiac output measurements by transcutaneous Doppler ultrasound: implications for noninvasive hemodynamic monitoring in the ED. Pediatric clavicular fractures: assessment of fracture patterns and predictors of complicated outcome.

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Taken together, our findings indicate that an immune response gene, poNACA, involved in innate immune regulation in P. Study of cholinesterases from different species using an inhibition analysis technique (structure variation of dialkoxyphosphate phosphoryl and cleaved groups). This retrospective study was performed on 77 eyes of 77 patients with primary or recurring subfoveal choroidal neovascularization secondary to AMD. Oral midazolam application should be generally preferred because it is more easily accepted by pediatric patients. This severe complication was most probably caused by embolisation from an atherosclerotic plaque of the thoracic aorta, as the nature of the surgery requires aortic manipulation. Therefore, closer investigation of the relationship between cytomegalovirus and age-related morbidities emerging in chronic HIV infection appears warranted. Velocity acceleration as a determinant of flow-mediated dilation.

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This is an observational descriptive report of cases collected by the authors during the years 1968-2006. These studies suggest functional conservation of homologous wood formation genes in gymnosperm and angiosperm taxa. The cantilever dynamics in single-frequency scanning probe microscopy (SPM) are undefined due to having only two output variables, which leads to poorly understood image contrast. A tactile alarm and two continuously informing tactile display designs were evaluated in an anesthesia induction simulation with anesthesiologists as participants. Flow cytometric assay and gel electrophoresis of DNA fragmentation also confirmed that Gyp induced apoptosis in the A549 cells. Personality traits in early phases of panic disorder: implications on the presence of agoraphobia, clinical severity and short-term outcome. Origins of altruism diversity I: The diverse ecological roles of altruistic strategies and their evolutionary responses to local competition. To clinically and genetically characterize ELE as the first manifestation of FMF. Fetal intra-abdominal cysts: accuracy and predictive value of prenatal ultrasound.

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Increased B-type natriuretic Peptide concentration is associated with reduced coronary vasoreactivity in patients with dilated cardiomyopathy but not in healthy young subjects. Here, we present an efficient and generalized image reconstruction method for PatLoc imaging using multiple SEMs without explicitly identifying the locations where SEM encoding is not unique. Sequential cross-sectional studies were performed during 1993-2007. Additional use of ultrasensitive copeptin improves diagnostic performance of conventional sensitive POCT assays overcoming lower sensitivities at the cost of a drop of clinical specificity. Curcumin (diferuloylmethane) inhibits cell proliferation, induces apoptosis, and decreases hormone levels and secretion in pituitary tumor cells. This albumin binging probably facilitated the retention and transport of PG in the lymph. Hence, native fluorescence of phenylalanine, tyrosine, and tryptophan can be used as a label-free methodology to facilitate quantification of peptides and proteins by LC-ESI-MS. Hospitals in sub-Saharan Africa are inundated with HIV-infected patients and tuberculosis (TB) is the commonest opportunistic infection in this sub-group. Numerous cognitive effects of fluctuations in ovarian hormones across the menstrual cycle have been previously identified.

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These results indicate that nude mice have higher than normal susceptibility to carcinogenesis under some circumstances. Confocal microscopy and TEM further showed that EGF1-EGFP-NP combined with TF and further transfected through the damaged endothelium. We tested a trait-based approach to link a soil disturbance to changes in invertebrate communities. Development of the human fetal hippocampal formation during early second trimester. This fragmentation was correlated to apoptosis induction which was confirmed by caspase-3 activation. Overall, both scanners produced good images with (18)F, (11)C, (89)Zr, (124)I, (68)Ga, and (90)Y. Non-tuberculous otomastoiditis is a severe ear disease with challenging considerations, and should be treated aggressively in order to avoid mometasone furoate inhaler dosing morbidity. All of these are important aspects of cancer progression, but the relationship between Eph receptors and cancer is complex and not fully understood.

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A computer simulation study was performed on prostates acquired at radical cystoprostatectomy. In Group B, 21 patients underwent 22 RFA-assisted hepatectomies in which 11 metastatic tumors, ten hepatomas, and two cholangiocarcinomas were removed. Collective motion of keratinocytes is involved in morphogenesis, homeostasis, and wound healing of the epidermis. The actions of menadione on ROS production and cell fate were compared with those of a non-cycling analogue (2,4-dimethoxy-2-methylnaphthalene (DMN)) using real-time confocal microscopy of isolated perfused murine pancreatic acinar cells. Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats. Introducing the description model file such as CellML is useful for generalizing the first point and partly second point, however, third point is difficult to handle. Orchiopexy without Transparenchymal Fixation Suturing: A 29-Year Experience.

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Results of Breathsavers Group meetings, conference calls and critically appraised topic summaries were used to construct potentially better practices. The present case suggests a pathomechanism for SNL that involves both an immunological background and an acute viral infection as triggers of exacerbation of aseptic meningitis. Novel diagnostic testing was performed to help narrow the differential diagnosis, and the patient responded well to pulmonary vasodilator treatment for progressive pulmonary hypertension. Preoperative administration of Lornoxicam attenuates the haemodynamic response to laryngoscopy and tracheal intubation in the elderly. Comparison of ankle plantar flexor activity between double-leg heel raise and walking. Patients taking cyclosporine, mycophenolate mofetil, and prednisone were randomly assigned to receive either rabbit antithymocyte globulin (1.5 mg per kilogram of body weight daily, 141 patients) during transplantation (day 0) and on days 1 through 4 or basiliximab (20 mg, 137 patients) on days 0 and 4. Transfection of cells with dominant negative Ras (RasN17) and Raf (RafS621A) mutant genes suppressed magnolol-induced ERK activity and p27KIP1 expression. This report presents three cases of urinary upper tract carcinomas producing granulocyte colony-stimulating factor (G-CSF), with high blood leukocyte counts and poor prognoses. In the group treated with botulinum toxin, low socio-economic status, lack of information about treatment options, fewer sessions and a shorter anhidrotic effect were associated with less satisfaction.

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Fluorescence microscopy suggested the high level expression of both DsRed and EGFP fluorescent proteins in spores and mycelia. Cholesterol was used to target the membrane for comparison with the well-known insertion model. Transcriptional activity of c-Myc is dependent on heterodimerization with partner protein Max. These results suggest that the response of LER to evaporative demand has a hydraulic origin, enhanced by the resistance to water flux at the soil-root interface. In this study, we investigated the effect of fluorescent-labeled hyaluronan nanocapsules containing polyhexanide biguanide and poly-L-lactic acid nanoparticles loaded with octenidine on primary human dermal microvascular endothelial cells, which play a major role in cutaneous wound healing.

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Recent family studies of schizophrenia which address the question of etiology are reviewed. TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill. Understanding how tinnitus sufferers consider and rank such options and how they might be influenced by their own perception of the severity of their tinnitus could help clinicians, researchers, and companies plan future efforts for approaching new treatments. Exogenous cortisol shifts a motivated bias from fear to anger in spatial working memory for facial expressions. Malignant peripheral nerve sheath tumours (MPNSTs) are the main cause of death in neurofibromatosis 1 adult patients.

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elegans mutants that experience caloric restriction because they are feeding-defective also exhibit elevated autophagy and decreased levels of fat deposits, as well as smaller cells and, consequently, a smaller body size. Calibration of laser ablation inductively coupled plasma mass spectrometry ethambutol tablet for quantitative measurements of lead in bone. Do Prostate Cancer Patients With Markedly Elevated PSA Benefit From Radiation Therapy?: A Population-based Study. For the II-VI semiconductors example, the band gap expands, the elastic modulus increases, the melting point drops, and the Raman optical phonons experience red shift associated with creation of low frequency Raman acoustic modes that undergo blue shift with decreasing the dimensional scale. Composting produced a degradation of the phytotoxic compounds, such as polyphenols, to give composts without a phytotoxic character. We sought to identify the genetic defect in a large, five-generation Chinese family with autosomal dominant progressive polymorphic congenital coronary cataracts and to examine the clinical features in detail.

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sequences of relations, are mined using distant supervision that potentially characterize a biomedical relation. Improving anharmonic infrared spectra using semiclassically prepared molecular dynamics simulations. For this reason, it would be useful to know whether vowel context has any systematic effect on consonant recognition in this population. Over the last decade a plethora of studies have investigated the responses of the retinal ganglion cells (RGCs) to electrical stimulation under a variety of stimulus configurations. Treatment for type 1 and part of type 2 often involves regular insulin injection. Although As concentrations in drinking water in Tarkwa were low, urinary As levels were comparable to those reported in highly As-affected are erythromycin and azithromycin the same drug areas in the world. Peritumoral cysts are benign nonneoplastic cysts that are found adjacent to extraaxial brain tumors such as meningiomas, schwannomas, craniopharyngiomas, and esthesioneuroblastomas. VEGF-A genotypes were analyzed using TaqMan SNP Genotyping Assays, Applied Biosystems.

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Contrary to the carcinogen-induced early changes towards a more relaxed uncoiled structure, as well as an apparent uncoupling between chromatin-DNA structural alterations and total RNA synthesis, could be first events in the carcinogenetic process. Experimental-theoretical part: Basic relationships and interpretation of the clinical radioiodine test. Of a series of 67 laparoscopic fundoplications, 20 with neurological compromise underwent FP placement at the time of surgery. More widespread implementation of Community Guide-recommended interventions (e.g., measures controlling access to alcohol and increasing prices) could reduce the frequency, intensity, and ultimately the prevalence of binge drinking, as well as the health and social costs related to it. Thus, the aim of this study was to compare clinical and surgical characteristics and immunohistochemical expression of E-Cad in APA, PC, and PA. Results of hierarchical linear modeling showed that only competitor orientation yielded a significant positive influence on knowledge creation, innovation behavior, or innovation diffusion. Not many patients fulfilling the criteria for an FSS, receive a formal diagnosis, and it is unknown which factors explain this discrepancy. Impact of autonomic neuropathy on left ventricular function in normotensive type 1 diabetic patients: a tissue Doppler echocardiographic study: response to Karamitsos et al. Gastroschisis is the most frequent cause of pediatric intestinal transplantation. Participants completed a Work and Well-Being Questionnaire to measure occupational stressors and the General Health Questionnaire-12 (GHQ-12) to measure stress at time point 1, and a follow-up GHQ-12 2 years later.

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Twenty human immunodeficiency virus (HIV)-positive subjects on ART and 20 controls (non-ART) were progressively monitored for three months. Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. Adding a degree of chemical restraint can make many procedures more pleasant for both practitioner and patient. The impact of first-generation biofuels on the depletion of the global phosphorus reserve. From March 1997 to March 2006, 102 patients with Stage T2-T4aN0M0 bladder urothelial carcinoma consecutively underwent transurethral resection of the bladder tumor followed by LCRT consisting of radiotherapy to the bladder (radiation dose 40 Gy) concurrent with two cycles of intravenous (20 mg/d for 5 days) or intra-arterial (100 mg) cisplatin.

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Second, the other epididymal fat pad in the rats in each experimental group was pooled for experiments in duplicate where liberated fat cells were separated in fat-cell size classes, which enabled comparisons of metabolic activities at the same fat-cell size. Publication bias was not a significant determinant of pooled accuracy. The synthesis, characterization, and host-guest chemistry of high-generation triazine dendrimers are described. Here, we test the hypothesis that spatial heterogeneity of the visual environment can influence sexual selection on colourful male secondary traits such that selective advantage is environment contingent aristocort cream generic . Preventive and cessation therapy of mental disorders in patients with the acute coronary syndrome. Atomic-detail information in the nanometer/second scale is still elusive to experimental techniques.

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CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. The majority of patients did not develop the ability to neutralize the mitogenic activity of their infecting isolate despite a significant increase in enzyme-linked immunosorbent assay titer in early convalescent-phase sera. Because depletion of Pontin leads to defects in the assembly and organization of microtubule arrays in egg extracts, our studies suggest that Pontin has a mitosis-specific function in regulating microtubule assembly. Synthesis, Structure of Nitrogen-Containing Phosphinogold(I) Ferrocenes. In this hybrid C-dot, PEI molecule played two key roles in the system - as a nitrogen-rich compound to passivate surface to enhance the fluorescence and as a polyelectrolyte lipitor 10 mg tablet to condense DNA. CCBE1 mutations can cause a mild, atypical form of generalized lymphatic dysplasia but are not a common cause of non-immune hydrops fetalis. The other is about the 2D graphic representation of protein sequence based on the 0-1 codes. Testicular germ cell tumours in Iceland: a nationwide clinicopathological study.

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The aim of the study was to investigate whether endoanal application of the ointment may lower the frequency of headaches without sacrificing effectiveness. After drainage of the abscess was performed, we conducted a colonoscopy to investigate the cause of the mass. A novel in situ immunotherapeutic strategy combining 3 different treatment modalities induced regression of disseminated follicular lymphoma how many mg of zyrtec can you take while pregnant , which correlated with systemic antitumor T-cell immunity. Postoperative pain was accessed during the first 8 hours and on the following 3 days using the visual analog scale (VAS), the 101-point numerical rate scale (NRS-101), and the four-point verbal rating scale (VRS-4). The value of 3-methoxy-4-hydroxy-mandlic acid (MHMA) for the differential diagnosis of neural tumors in childhood. As drug-eluting stents are extensively used to treat all lesions, more efficacious agents and improved stent platforms are required.

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