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Metoprolol is a beta-blocker indicated for treatment of high blood pressure, angina, heart attacks, arrhythmia. This medication influences autonomic nervous system which stipulates increased heart rate by blocking its receptors and thus reducing abnormally rapid heart rhythms. It also diminishes myocardial irritability, cardiac output and causes other effects.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Metoprolol is a perfect remedy. Its target is to struggle against high blood pressure. It also can be used in the treatment of chest pain, heart attacks. Metoprolol acts by slowing the heart rate and relaxing the blood vessels. It is beta blocker. Metoprolol is also known as Toprol-XL, Metoprolol, Protomet, Lopresor, Lopresar. Generic name of Metoprolol is Metoprolol Tartrate. Brand names of Metoprolol are Toprol-XL, Metoprolol.


Take Metoprolol tablets orally with water. Take Metoprolol once or twice a day at the same time. Do not crush or chew it. If you want to achieve most effective results do not stop taking Metoprolol suddenly.


If you overdose Metoprolol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Metoprolol overdosage: fainting, difficulty, breathing or swallowing, swelling of the hands, feet, ankles, or lower legs, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Metoprolol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Metoprolol if you are allergic to Metoprolol components. Do not take Metoprolol if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Metoprolol if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Metoprolol in case of taking cimetidine (Tagamet), clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem), hydroxychloroquine, paroxetine (Paxil), propafenone (Rythmol), quinidine (Quinaglute, Quinidex), ranitidine (Zantac), reserpine (Serpalan, Serpasil, Serpatab), ritonavir (Norvir), terbinafine (Lamisil),and thioridazine (Mellaril), bupropion (Wellbutrin). Be careful with Metoprolol if you have allergies to medicines, foods, or other substances. Be careful with Metoprolol if you suffer from or have a history of heart or liver disease; diabetes; severe allergies; or an overactive thyroid gland (hyperthyroidism), slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), had asthma or other lung disease. Use Metoprolol with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Avoid machine driving. Do not stop taking Metoprolol suddenly.

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MKC-231, a choline-uptake enhancer: (1) long-lasting cognitive improvement after repeated administration in AF64A-treated rats. We observed lower basal plasma cortisol levels (borderline statistical significance) and a lower expression of corticosteroid receptors and GILZ in FM patients when compared to healthy controls. In some cases, circulating antibody to acetylcholine receptor is present and the amount of receptor in the end-plates is decreased. The current review focuses on recent developments in the field of molecular MRI to characterise different stages of atherosclerotic vessel wall disease. The limited but available evidence reported does indicate that smoking cessation interventions specifically targeted at Indigenous populations can produce smoking abstinence. Bimodal lasing with similar pumping thresholds was experimentally observed, and polarization properties of the two modes were used to unambiguously identify them with theoretically predicted modes. Effects on the thrombin-like enzyme batroxobin on thrombin-induced DIC in rats. HBV DNA vaccines, with their strong ability to induce cell-mediated immune responses, offer an attractive option.

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The dopamine system is the main target of antipsychotic and psychostimulant drugs. Clara cell 10-kD protein (CC10) is well known to be an immuno-suppressive protein secreted from airway epithelial cells after inflammatory stimulation and is involved in the development of allergic disorders. Sub-micrometer resolution proximity X-ray microscope with digital image registration. Five adult female elephants were immobilized and neck collars were fitted with tracking devices. Yet these assumptions are rarely considered in assessing the validity of the prevailing hypotheses. Behavioral effects of chronic administration of psychoactive drugs to anxious patients. Race did not contribute to disparate acceptance and rejection rates among African Americans and Caucasians. Immunohistochemistry confirmed the metastatic tumour originating from the primary papillary adenocarcinoma of the thyroid gland. In (CBA X C57BL)F1 mice the suppressive acitivty of bone marrow remains unchanged over the same time period. The catalytic hydrogenation of nitriles to primary amines represents an atom-efficient and environmentally benign reduction methodology in organic chemistry.

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Coherence vortices in Mie scattered nonparaxial partially coherent beams. Trichomonadosis in women following total hysterectomy and adnexectomy (preliminary report). The introduction of standards for the evaluation of syncope in the ED would be helpful. The QuickRead CRP test is easy to use, provides reliable results and reduces the need for antibacterial therapy. Correlation of World Health Organization classification of thymic epithelial tumors to their CT features. The downstream cytokines IL-18 and sRANKL/OPG in MM patients were higher than that in control group. Ethical issues raised by direct-to-consumer personal genome analysis and whole body scans: discussion and contextualisation of a report by the Nuffield Council on Bioethics.

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Herbicide 2,4-D at a dosage of 500 mg l-1 stimulated the proliferation of the heterotrophic bacterial community present in the water of three fish ponds over a period of one year. We investigated this in terms of key personality/temperament traits of Reactive and Effortful Control, Resiliency, and Emotionality. A comparison of sennosides-based bowel protocols with and without docusate in hospitalized patients with cancer. To prepare nanoemulsion-encapsulated MAGE1-Hsp70/SEA and to evaluate its anti-tumor effects in mouse. The results show that SSBs in LEC rat brain cells are induced at a lower concentration of copper than are SSBs in hepatic cells. Moreover, Hfq loss-of-function inhibited the expression of sRNA-TEG49 in mutant-type S.

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Active Acetylcholinesterase Immobilization on a Functionalized Silicon Surface. Biological and clinical significance of glutamic oxalacetic and glutamic pyruvic transaminases. However restenosis remains a major limitation to the effectiveness of stents. The mean size of an ethanol one-component cluster and that of an ethanol/water binary cluster are expressed as a maximum at the interface. Treatment of coronary arteriosclerosis by weak-current galvanization of the area of the heart. Hyperglycemia raises the threshold of levosimendan-induced postconditioning, while milrinone-induced postconditioning is not influenced by hyperglycemia.

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Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. HSV-1 (McKrae) engineered virus constitutively expressing enhanced green fluorescence protein (GFP) was efficiently transmitted in both a retrograde and an anterograde manner. We developed a computer-based tutorial and a posttest on ECG interpretation for training residents and determining competency. In spite of successful stent placement, some patients complain of ongoing dysphagia and vomiting. The effect of reserpine on the intracellular distribution of catecholamines in the brain stem of the rabbit. The technique is robust and exhibits consistent performance for different object configurations and orientations. Multivariable logistic regression analysis of a large trauma cohort definitively establishes that gender is not independently associated with mortality after blunt trauma in humans.

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Cetuximab treatment caused a reduction in the proliferation rate of HNSCC cell lines, whereas the growth of HNSCC-derived CAF cultures was unaffected. Regulatory role of charged clusters in the N-terminal domain of BetP from Corynebacterium glutamicum. Holo and apo-transferrins interfere with adherence to abiotic surfaces and with adhesion/invasion to HeLa cells in Staphylococcus spp. Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children. Preparation and biological characterization of isomeric 188Re(V) oxocomplexes with tetradentate S4 ligands derived from meso-dimercaptosuccinic acid for labeling of biomolecules. To evaluate the effect of Armillariella tabescens on cisplatin chemotherapy-induced gastrointestinal tract reaction. Thus, no evidence of avoidance of inbreeding was observed in the closed captive groups of rhesus monkeys studied.

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An important role for polymorphic cytochrome P450 2D6 (CYP2D6) in the metabolism of IAA drugs of abuse has been revealed by recent studies, suggesting that variations in IAA metabolism, pharmaco- or toxicokinetics and dynamics can arise from distinct CYP2D6 status, and CYP2D6 polymorphism may represent an additional risk factor in the use of these IAA drugs. The severity of the threat expressed and the risk posed by the adolescent in question were evaluated. Lactoferrin, an iron-binding glycoprotein secreted from glandular epithelial cells into body fluids, promotes skin wound healing by enhancing the initial inflammatory phase. Estimated Global, Regional, and National Disease Burdens Related to Sugar-Sweetened Beverage Consumption in 2010. Topical Review: Advancing Research on the Transition to Adult Care for Type 1 Diabetes. Chondroid tissue first manifests during late embryogenesis, appears to differentiate from pre-existing chordoid tissue, and has the histological and histochemical characteristics of cartilage.

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A dog histopathologically diagnosed with hepatocellular carcinoma (HCC) showed very high serum alkaline phosphatase (ALP) activity. In contrast, noninvasive carcinoma cells as well as normal bladder epithelial cells lacked the capacity to erode and penetrate the extracted matrix of the articular cartilage. Further progress is anticipated through the integration of chemopreventive agents into the adjuvant treatment. We conclude that spinal and/or ganglionic mechanisms may generate a component of the sympathetic hyperactivity exhibited by SHR. Marrow suppression was dose-limiting and occurred in 5/6 evaluable patients receiving more than 30 mg in the short-term infusion schedule and 8/10 evaluable patients receiving more than 20 mg in the protracted infusion schedule. The medical records of all patients who underwent TS for sphincter of Oddi dysfunction and pancreas divisum at the Medical University of South Carolina between January 2001 and December 2005 were reviewed. Direct gene transfer of NGF in the diabetic rat hearts improved impaired cardiac sensory innervation and function, determined by electrophysiological activity of cardiac afferent nerves during myocardial ischemia.

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Most patients present with mitral stenosis of varying degree of severity, and rarely present with severe mitral regurgitation as seen in our patient. Herein, we will detail the host-pathogen sumycin 500 mg relationship of HIV and mucosal barriers in both of these scenarios. These data suggest a protective role of adiponectin in diminishing microvascular organ-specific endothelial cell activation during sepsis. Evidence-based treatment guidelines recommend low molecular weight heparin (LMWH) monotherapy for cancer-associated venous thromboembolism (VTE). The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood products (HWP) to meet greenhouse gas monitoring commitments and climate change adaptation and mitigation objectives. As herbal and food supplement producers are left to their own means to determine the safety and purity of their products prior to marketing, disturbingly often good marketing practices currently in place are ignored and content is largely undocumented. Neuronal apoptosis and diminished cell function were identified by TUNEL (terminal deoxynucleotidyl transferase-mediated BrdUTP nick end labeling) and choline acetyltransferase staining, respectively. We investigated the cellular localization and progressive changes of corticotropin releasing factor (CRF) in the mouse hippocampus, during and after pilocarpine induced status epilepticus (PISE) and subsequent epileptogenesis. Evaluation of three mRNA markers for the detection of lymph node metastases. These results indicate that Pax9 and Shh expression are altered when the TGF-beta3 gene is deleted and suggest that Pax9 and Shh may be involved in the TGF-beta3 regulation of normal palatal fusion.

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This study was conducted to better understand the NSNHEs as patients actually experience them in their daily life, and how they impacted functioning and well-being. Endovascular thrombolysis, with or without mechanical clot removal, may be beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT) who have a poor prognosis despite treatment with heparin. In end-stage occlusive vascular disease, the limiting factor in determining how distal an amputation can be performed is whether or not the stump will heal. alpha1,4-Glucosidase-albumin polymers: in vitro properties and advantages for enzyme replacement therapy. In order to increase precision for subgroup estimations the design was stratified with over-sampling of Malays, Indians and those aged 65 years and above. We assessed the level of awareness of vitamin D deficiency among at-risk patients in order to identify groups most in need of education. In this work, we provide a segmentation and classification method to extract potential lesions, as well as adipose, fibroglandular, muscle and skin tissue in reconstructed DBT images that serve as anatomic priors during NIRS reconstruction. Filling in the Gaps: Priming and the Ethics of Pharmaceutical Advertising.

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Random and patterned misclassification and bias in case-control studies. Optic neuropathy after vitrectomy for retinal detachment: clinical features and analysis of risk factors. The catalytic machinery of a key enzyme in amino Acid biosynthesis. These rescuers require special attention during CPR training, with an emphasis on correct body positioning and use of body weight for CCs. Removing the neglect from neglected tropical diseases: the Rwandan experience 2008-2010. The aim of this study was therefore to analyze plantar pressure distribution in carbon fiber foot orthoses in comparison to standard insoles of commercially available cycling shoes.

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New Age of Fishes initiated by the Cretaceous-Paleogene mass extinction. Radiographic highlights: traumatic rupture of the thoracic aorta. Informant consensus was determined for each of the plants mentioned. Application of live-cell RNA imaging techniques to the study of retroviral RNA trafficking. To our knowledge, this is the first report of Sarcocystis in celexa drug overdose Apodemus agrarius chejuensis captured in Korea. To determine whether growth rate (GR) of cutaneous melanoma predicts the histological sentinel lymph node (SLN) positivity. In the field of motor development, a question exists whether spontaneous activity in early infancy serves as a precursor to later-emerging goal-directed behaviors.

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This review presents a brief history of the discovery of 5S rRNA and studies of its origin and localization in the ribosome. Mosaic expression of green fluorescent protein (GFP) in the lens is a useful marker for monitoring macromolecule distribution between fiber cells and for constructing three-dimensional images of living lens cells. Elevated plasma homocysteine in association with decreased vitamin B(12), folate, serotonin, lipids and lipoproteins in depressed patients. Depression in patients with alcohol use disorders: Systematic review precose dosing and meta-analysis of outcomes for independent and substance-induced disorders. The concentration of tetracycline in gingival fluid peaked at 3 1/2-7 h achieving average levels typically in the range of 5-12 micrograms/ml.

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