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Lopam (Lorazepam)

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Lopam belongs to a group of drugs called benzodiazepines. Lorazepam affects chemicals in the brain that may be unbalanced in people with anxiety. Lopam is used to treat anxiety disorders. Lopam may also be used for purposes not listed in this medication guide.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

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Skelaxin, Danocrine, Parlodel, Levitra, Periactin, Vermox, Feldene

Also known as: Lorazepam


Lopam tablets should be taken in the way your doctor prescribed them. Don’t take more or less Lopam than prescribed without first talking with your doctor.


Lopam is usually taken two or three times daily. These doses are usually spread out at equal intervals. However, when Lopam is used for insomnia, it’s usually taken just once at bedtime.

Taking Lopam with food

You can take Lopam with or without food. If it upsets your stomach, try taking it with food to help decrease this side effect.

Can Lopam be crushed?

Yes, Lopam can be crushed. Some Lopam tablets may also be split. If you’d like to split your tablets, ask your pharmacist if it’s safe to do so.


ake this medication by mouth with or without food as directed by your doctor. The dosage is based on your medical condition, age, and response to treatment.

If directed by your doctor, use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day.


In cases of a suspected Lopam overdose, it is important to establish whether the patient is a regular user of Lopam or other benzodiazepines, since regular use causes tolerance to develop. Also, one must ascertain whether other substances were also ingested.

Signs of overdose range through mental confusion, dysarthria, paradoxical reactions, drowsiness, hypotonia, ataxia, hypotension, hypnotic state, coma, cardiovascular depression, respiratory depression, and death.

Early management of alert patients includes emetics, gastric lavage, and activated charcoal. Otherwise, management is by observation, including of vital signs, support and, only if necessary, considering the hazards of doing so, giving intravenous flumazenil.

Patients are ideally nursed in a kind, nonfrustrating environment, since, when given or taken in high doses, benzodiazepines are more likely to cause paradoxical reactions. If shown sympathy, even quite crudely feigned, patients may respond solicitously, but they may respond with disproportionate aggression to frustrating cues. Opportunistic counseling has limited value here, as the patient is unlikely to recall this later, owing to drug-induced anterograde amnesia.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Lopam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Lopam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Lopam Injection.

Extreme caution must be used when administering Lopam Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Lopam injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Lopam Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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Indium(i) iodide was found to catalyze the formal alpha-addition of an alpha-methylallylboronate to various N-acylhydrazones, in the presence of an alcohol additive, to afford the corresponding anti-alpha-adducts with high regio- and diastereoselectivity in high yields. EEG alpha-biofeedback training: an experimental technique for the management of anxiety. The effect of a chitosan-gelatin matrix and dexamethasone on the behavior of rabbit mesenchymal stem cells. Reasons for not initiating osteoporosis therapy among a managed care population. Among the identified persons were one emperor, two United States presidents, a legendary composer, a world-renowned medical doctor, an outstanding athlete and an extraordinary entertainer. The anatomy and physiology of the perionychium is presented in detail. Elevated low shear blood viscosity with erythrocyte aggregation and elevated high shear blood viscosity with reduced erythrocyte deformability might be important and potentially treatable factors in the etiology or progression of diabetic macroangiopathy. The marginal leakage was significantly reduced or eliminated in restoration where the enamel at the cavosurface angle was etched and after insertion of the restoration.

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A dialectic of cooperation and competition: solidarity and universal health care provision. The original exponential piston-flow model was modified to take land-use distribution into account and applied to predict the evolution of atrazine concentration in a series of springs draining a fractured sandstone aquifer in Luxembourg, where despite a nationwide ban in 2005, atrazine concentrations still had not begun to decrease in 2009. Association of selenoprotein S gene polymorphism with ischemic stroke: how strong is the evidence?. A total of 2,200 subjects, 1,111 women and 1,089 men, aged 25 to 75 years. On the determination of esterized fatty acids in blood serum with special reference to the hydroxamic acid method. Citrulline level is a potent indicator of acute rejection in the long term following pediatric intestinal/multivisceral transplantation. Nowdays, it is common seen that criminals tend to use the lock-against-theft for motorcycle to harm others as a tool. Therapy of inflammatory stomach diseases and ulcers--practical findings. In countries like Finland and Norway, rapid nationwide implementation has been obtained.

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The nocturnal behavior of caged rhesus monkeys (Macaca mulatta). We have demonstrated proof of principle for the determination of bowel ischemia using 3-CCD image enhancement. Although the loss of muscle mass is associated with the decline in strength in older adults, this strength decline is much more rapid than the concomitant loss of muscle mass, suggesting a decline in muscle quality. The muramidase content of macrophages in foreign body reactions and lepromatous leprosy varied and most multinucleate cells in these lesions gave a negative reaction. We conclude that the biglycan/decorin mixed double knockout mouse is a model of dystocia and delayed labor onset. However, tumors are often resistant to radiotherapy due to an enhanced DNA repair activity. However, several studies have shown that sugars and lipids are mainly responsible for Mtb pathogenesis and resistance to numerous drugs. Controlled prospective clinical trials using advanced imaging techniques are necessary for a complete assessment. The process of mixing a radiopaque substance with a local anesthetic agent combined with air will in itself dissolve existing adhesions during the tapping of the joint, as a result of which this diagnostic procedure will turn into therapy.

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Retinal dysfunction in combined methylmalonic aciduria and homocystinuria (Cblc) disease: a spectrum of disorders. Children were required to walk towards and intercept a stationary ball or a moving ball, with either their impaired or non-impaired arm. The effectiveness of using HyperHAES hypertonic isooncotic plasma solution to achieve stable intracranial hypotension can differin gel get rid of acne scars in endoscopic endonasal transsphenoidal adenomectomy as an alternative to the invasive external lumbar drainage. Spectroscopic characterization of a higher plant heme oxygenase isoform-1 from Glycine max (soybean)--coordination structure of the heme complex and catabolism of heme. Relaxation and skin conductance feedback in the control of reactions to cognitive tasks. To determine the allelic and genotypic frequencies of the APOE gene in a sample of a population group in Peru. Furthermore, we will discuss when to refer for clinical genetic evaluation as well as the current and future merits of genetic evaluation of children with osteoporosis. This was revealed by the capacity of cell-free culture supernates to recognize alloantigens as measured in the PAR assay.

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Induced thermotolerance under nonisothermal treatments of a heat sensitive and a resistant strain of Staphylococcus aureus in media of different pH. Molecular profiles of the mouse postnatal development of the esophageal epithelium showing delayed growth start. A study of the causes and prevention of edema of the arm following radical mastectomy. Our case not only highlights the importance of close cutaneous surveillance and a low threshold for biopsy in patients with breast-conserving surgery and radiation therapy, but also raises the possibility of radiation as the inducement of cutaneous LCH. Need for national/regional guidelines and policies in India to combat antibiotic resistance. After sympathetic denervation of the gland the secretory response to tyramine and phenylethylamine was absent, the response to dopamine and ephedrine decreased and the response to adrenaline and noradrenaline increased. Practical understanding and use of surface enhanced Raman scattering/surface enhanced resonance Raman scattering in chemical and biological analysis.

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Cervical cancer incidence and mortality have decreased dramatically over the past 50 years in countries with access and resources to provide frequent screening, evaluation, and treatment of high-grade cervical cancer precursors. It produces a cataleptic-like state where the patient is dissociated from the surrounding environment by direct action on the cortex and limbic system. Although previous work showed that most pelvic floor symptoms correlated poorly with levels of early prolapse, longitudinal analysis suggests that vaginal descent progression over time is positively associated with various bladder, bowel, and prolapse symptoms in postmenopausal women with stages I-II prolapse. The lowest energy states exhibit spin waves, domains, and localization, depending on the angular momentum. On the gestation of the black salamander of the Alps, Salamandra atra Laur.

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Clotrimazole is an azole derivative with promising anti-cancer effects. Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: effect of fenofibrate treatment. All these activities require a multidisciplinary approach to ensure integration with hospital-wide emergency planning efforts. In the present study, the effects of methimazole (a major anti-thyroid drug) administration to rat dams on the development of cerebellum of their pups were investigated with morphological, morphometrical and functional procedures. Of these, 5-azaorotate was the most effective and could serve as the vasotec iv dose prototype of a potential antimalarial. However, nearly all of these new techniques concomitantly decrease genome quality, primarily due to the inability of their relatively short read lengths to bridge certain genomic regions, e.g., those containing repeats. Scaling up training and education for the Health Workforce--international collaboration. They had high anxiety and fear of loss, bore much burden of care, and faced many difficulties because of limited resources. We studied a case of CST that evolved from osteomyelitis and orbital cellulitis in a patient who had a rapid loss of vision to the level of no light perception. Central obesity is a prerequisite for the diagnosis of metabolic syndrome (MetS).

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