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Depakote (Divalproex)

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Depakote is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches.

Other names for this medication:
Desval, Dicorate, Dilex, Diproex, Discern, Disorate, Divaa, Divalin, Divalprid, Divalpro, Divalproex, Divalrate, Dixval, Drvel, Elival, Encorate, Epilex, Genval, Jydival, Napilex, Navalin, Nepilex, Proval, Sezex, Sodaval, Spikalon, Trival, Valance, Valcontin, Valcort, Valop, Valpex, Valpip, Valporil, Valporiv, Valporl, Valpret, Valprol, Valprosh, Valtec, Valvo, Velpo, Velze, Zorat, Zoret

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Also known as: Divalproex


Depakote is a perfect remedy in struggle against seizure disorders. Depakote acts by increasing the amount of a certain natural substance in the brain. Depakote is also known as Valproate semisodium, Divalproex sodium, Valproic acid, Divaa. It is anticonvulsant. Generic name of Depakote is Divalproex Sodium. Brand names of Depakote are Depakote, Depakote ER, Depakote Sprinkles.


Take Depakote tablets orally with food. Take Depakote at the same time every day with water. Do not crush or chew it. If you want to achieve most effective results do not stop taking Depakote suddenly.


If you overdose Depakote and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Depakote overdosage: shallow, breathing, weak pulse, sleepiness, feeling drowsy, loss of consciousness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Depakote are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Depakote if you are allergic to Depakote components. Do not take Depakote if you are pregnant, planning to become pregnant, or are breast-feeding. Do not take medicines which cause sleepiness. Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Depakote if you suffer from or have a history of vomiting, extreme tiredness and/or irritability; episodes of confusion and loss of ability to think and understand, especially during pregnancy or after childbirth; coma (loss of consciousness for a period of time); difficulty coordinating your movements; human immunodeficiency virus (HIV); cytomegalovirus (CMV; a virus that can cause symptoms in people who have weak immune systems); hyperlipidemia (higher than normal amount of fats in the blood); or kidney disease, urea cycle disorder, mental retardation. Be careful with Depakote if you take aspirin, barbiturates such as phenobarbital and seconal blood thinners such as Coumadin, Cyclosporine (Sandimmune, Neoral), Nortriptyline (Pamelor), clonazepam (Klonopin), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), phenytoin (Dilantin), and Primidone Mysoline), Rifampin (Rifater, Rimactane), Sleep aids such as Halcion, Tolbutamide (Orinase),Tranquilizers such as Valium and Xanax, Zidovudine (Retrovir), Amitriptyline (Elavil), carbamazepine (Tegretol), Merrem IV (meropenem for injection). If you experience drowsiness and dizziness while taking Depakote you should avoid any activities such as driving or operating machinery. Avoid alcohol while taking Depakote. Avoid being dehydrating. If you are going to have a surgery, be careful with Depakote. It can be dangerous to stop Depakote taking suddenly.

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