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Cymbalta (Duloxetine)

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Cymbalta is good for treating depression, anxiety, and some forms of long-term pain, but it's more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.

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Also known as: Duloxetine


Generic Cymbalta is developed by medical scientists to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors. Generic Cymbalta affects chemicals in the brain that may become unbalanced and cause depression. Generic Cymbalta is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.


Take Generic Cymbalta with a full glass of water with or without food. It is recommended to take Generic Cymbalta at the same time each day. Do not crush, chew, break, or open a delayed-release capsule. Swallow the tablet whole. If you want to achieve most effective results do not stop using Generic Cymbalta suddenly.


If you take an overdose of Cymbalta, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cymbalta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Cymbalta if you are allergic to Generic Cymbalta components. Do not take Generic Cymbalta if you're pregnant or you plan to have a baby, or you are a nursing mother. This medication can cause birth defects. Tell your doctor right away if you become pregnant during treatment. Be very careful with Generic Cymbalta if you're pregnant or you plan to have a baby. Do not take Generic Cymbalta if you are breast-feeding. Do not take Generic Cymbalta together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Generic Cymbalta. After you stop taking Generic Cymbalta, you must wait at least 5 days before you start taking an MAOI. Generic Cymbalta can be not safety for children and people younger than 18 years old. Do not take Generic Cymbalta if you have any of these conditions:liver or kidney disease, seizures or epilepsy, a bleeding or blood clotting disorder, glaucoma, bipolar disorder (manic depression), a history of drug abuse or suicidal thoughts.Be careful if you drive or do anything that requires you to be alert. Generic Cymbalta may impair your thinking or reactions. Avoid alcohol. It can be dangerous to stop Generic Cymbalta using suddenly.

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Outcome after coronary artery bypass grafting and percutaneous coronary intervention in patients with stage 3b-5 chronic kidney disease. This model successfully accounts for the observed non-equivalence of anterior and posterior skin, and also explains the different regeneration behaviour of anterior and posterior half limbs, the limited regeneration of double anterior limbs, and the pattern expansion and contraction shown by regenerates from double posterior limbs. Signaling pathways, and specifically the signaling pathway of calcium, have been widely implicated in the regulation of a variety of signals in plants. If it is possible to remit the infection, the prognosis for recovery of motor and sensory function is better than in cases with traumatic spinal cord injury. Thymoma is extremely rare within the pediatric age range, which could lead to delayed diagnosis. In vitro activity of Lantana camara, Alpinia zerumbet, Mentha villosa and Tagetes minuta decoctions on Haemonchus contortus eggs and larvae. These activities were detected in hemispheres both contralateral and ipsilateral to the stimulation, and were estimated to be located around the tongue SI. Protein metabolic status of acute myocardial infarct patients before and after fentanyl and droperidol arrest of the pain syndrome. The TLR1-1805GG polymorphism in B burgdorferi RST1-infected patients was associated with stronger Th1-like inflammatory responses, an environment that may set the stage for antibiotic-refractory arthritis.

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Acute hypertension management in the critical care unit: a case review of aortic arch repair. The generation of the endothelial specific cdc42-deficient mice and the effect of cdc42 deletion on the angiogenesis and embryonic development. Whether agents that modulate high-density lipoprotein cholesterol are effective in reducing stroke is still the subject of clinical study. Within 10 min of IL-11 treatment, p-STAT3(tyr705) was localized inside the nucleus of both the cell can you buy diflucan over the counter in canada lines but, there was enhanced co-localization of protein inhibitor of activated STAT1/3 (PIAS1/3) and p-STAT3(tyr705) in HTR-8/SVneo cells and not in JEG-3 cells. The GMAWS was reliable and gauged both physical and cognitive aspects of AWS.

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The newly classified family Hytrosaviridae comprises several double-stranded DNA viruses that have been isolated from various dipteran species. Quantification of the expression of such genes requires normalising qPCR data using reference genes with stable expression in the system studied as internal standards. IL-6 elevation also resulted in an abnormal change in the shape, length and distributing pattern of dendritic spines. Antimicrobial proteins (AMP) are small endogenous proteins which are capable of rapidly inactivating microorganisms at low micro- and nanomolar concentrations. Some diseases may be accompanied by an eczematiform dermatitis (phenylketonuria, anomalies of histidin metabolism). Both noradrenaline appearance rate and noradrenaline clearance increased significantly with increasing energy intake and were a more sensitive indices than the plasma noradrenaline concentrations which rose, but not significantly. All patients who had a strictureplasty of the small bowel between 1985 and 2010 were identified from a prospective database. Development and changes with age of detrusor overactivity in spontaneous hypertensive rats as observed by simultaneous registrations of intravesical and intraabdominal pressures.

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All-trans retinoic acid inhibits migration, invasion and proliferation, and promotes apoptosis in glioma cells in vitro. Spermatozoa isolated from semen samples of boars contained all transcripts investigated, whereas oocytes contained only CREM, H1, TAF1, and TBP mRNAs. The treatment of patients with type 2 diabetes in the hospital is very different from their treatment at home. Biochemical experiments confirm that this C-terminal fragment of Sec16 binds to the cytosolic domain of Sec12. Sixty eyes of 30 myopic patients were prospectively recruited to a randomized fellow eye study. The data also replicate the differential cue utilization by male and female 10-year-olds. The value of ultrasonography and computed tomography in diagnosis is still to be proven. The development of the female reproductive system during adolescence.

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Anaemia occurs early in the course of diabetes-related chronic kidney disease (CKD). Thirty-six scenarios were assessed for each non-invasive test strategy, which varied the sensitivity of biopsy, the anxiety associated with biopsy, sensitivity and specificity values and whether or not the biopsy was percutaneous or transjugular. The presented data contribute to the evaluation of the health status of birds in the German North Sea. This balance is maintained by a complex interplay between the dietary intake of nutrients, the hormonal response to the nutrients, and their effect on both the liver and adipose tissue. In one case a discrete pneumothorax was observed in radiographic imaging. First report of the epiphytic benthic dinoflagellates Coolia canariensis and Coolia malayensis in the waters off Jeju Island, Korea: morphology and rDNA sequences. But in noncardiac shock cases, the increased BNP did not correlate with heart function, therefore it could not replace the Swan-Ganz catheter data to guide the treatment in these patients.

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