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Cartan (Losartan)
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Cartan

Cartan belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Cartan prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Cartan slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.

Other names for this medication:
Angilock, Aratan, Cardoplus, Cardzaar, Cormac, Corodin, Eklips, Giovax, Lifezar, Lopress, Lortaan, Losadel, Losalet, Losan, Losapot, Losapres, Losart, Losartan, Losartec, Losazid, Lospre, Lostan, Loxibin, Lozar, Myotan, Niten, Ostan, Ozarium, Portiron, Ranlozar, Repace, Sanipresin, Sarilen, Sarlo, Sartaxal, Sartens, Sarve, Satoren, Tacardia, Tensiohess, Zartan

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Uroxatral, Lozol, Priligy, Benemid, Cordarone, Diovan, Nimotop, Loxitane, Arcoxia

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Also known as: Losartan

Description

Cartan is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Cartan is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Cartan is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Cartan reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease

Dosage

Take Cartan tablets orally with or without food. Do not crush or chew it. Take Cartan once or twice a day at the same time. If you want to achieve most effective results do not stop taking Cartan suddenly.

Overdose

If you overdose Cartan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Cartan overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Cartan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Cartan.

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We report here that mice lacking Foxl2 also show defects in postnatal growth and embryonic bone and cartilage formation. There were no clinic visits or dietitian contacts during the study period. The proposed approach can be applied to any type of high dimensional dataset. Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Efficacy of an Iranian herbal preparation (Lax-Asab) in treating functional constipation: A randomized, placebo-controlled clinical trial. A secondary analysis of a 1-y randomized calcium and activity trial in 178 children was conducted.

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Even though it has been proposed that IFN type I is required for adjuvanticity to influenza vaccines, we found that MF59 and Pam3CSK4 were not good inducers of IFN-related innate immunity pathways. Networking for applied field epidemiology - Eastern Mediterranean Public Health Network (EMPHNET) Conference 2011. Ephrin-A5-mutant mice are, therefore, a unique model to study the effects of reduced thalamic innervation on the assembly of cortical circuits and sensory processing. For smooth operation, the suction performance must be superior to the cutting performance. In addition to changes to taste, participants described sensory and hedonic changes which influence overall flavour perception and food enjoyment.

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2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. Cardiac amyloidosis (amyloid cardiomyopathy) is a systemic disorder of protein metabolism with the predominant deposition of amyloid (fibrillar beta-protein) in myocardium and coronary artery walls. An important conclusion of this work is that diffusion in nanoporous materials can never be described by one single effect so that we need to distinguish different loading regimes to describe the diffusion over the entire loading range. Regional concentrations of noradrenaline and dopamine in the frontal cortex of the rat: dopaminergic innervation of the prefrontal subareas and lateralization of prefrontal dopamine. Thus, our data reveal a new facet of Vpr-induced cell cycle arrest involving previously unrecognized abnormal rearrangements of multiprotein assemblies containing key cell cycle regulatory proteins. Primary outcomes were operative mortality and major adverse cardiac and cerebrovascular events comprising death before discharge, myocardial infarction and neurologic damage. In 11 pediatric patients newly diagnosed with IgAN, exploration for infectious foci showed severe oral infection, including dental caries and apical periodontitis, in many. Cap-assisted colonoscopy has improved adenoma detection in some but not other studies. Acquired immune deficiency syndrome case reporting system - Addressing the problem of reporting delay. The proliferation maxima of epithelial cells were delayed for 24 h.

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Quantifying continuous exercise using the ratio of work completed to endurance limit associated with exercise-induced delayed-onset muscle soreness. Dental lead levels in children from two different urban and suburban areas of Turkey. Hyperdense middle cerebral artery sign among patients with severe ischemic attack on ultra-early phase. Analysis of social networks supporting the self-management of type 2 diabetes for people with mental illness. Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis. To characterize the expression pattern of GPR56 in the developing cerebral cortex, we developed a mouse monoclonal antibody against mouse GPR56. Interestingly, Skp2-mediated p27 degradation was not essential for G1/S or S/G2 transition as preadipocytes shifted from quiescence to proliferation during adipocyte hyperplasia. Radiation injuries of the TMJ are tolerable in both 3D-CRT and IMRT groups, and 3D-CRT is a more economic choice for patients who can not afford IMRT.

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Imiquimod-induced subacute cutaneous lupus erythematosus-like changes. We compared the diagnoses after diagnostic laparoscopy and those after pelvic examination and imaging modalities such as ultrasound or computed tomography (CT), and we then checked the final pathologic diagnoses after operation. Perivascular sympathectomy of the vertebral artery and its effect on the cervicovestibular syndrome. Effect of insulin and substances depressing insulin synthesis (alloxan and dithizone) on the sensitivity of choline-reactive structures of the central nervous system. Secondary data analysis of National Family Health Survey-3 (NFHS-3) was undertaken to study demographical variations in tobacco use between urban slum dwellers and non-slum dwellers in eight Indian cities. Intracardiac total cavopulmonary connection in an asplenic adult male 12 years after Glenn procedure for total anomalous pulmonary venous return (1b). The aim of this study was to assess systemic presence of RA-AAB in patients without RA who had oral or lung mucosal inflammation.

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Acute occlusion of the internal carotid artery without anterior collateral circulation. The impact of geographic market definition on the stringency of hospital merger control in Germany and the Netherlands. These data show that the GPR30 agonist G-1 mitigates the adverse effects of oestrogen loss on LV remodelling and the development of diastolic dysfunction in the study rats. All lung transplant patients who underwent single- or double-lung transplantation who received rFVIIa in the 5-year period, from January 2005 to June 2011, were included. This review provides an overview on this subject by dividing skin lesions into three main groups: (1) skin disorders due to vascular changes (dilatation, occlusion and inflammation), (2) unspecific (e.g.

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