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Calzem (Calcitriol)
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Calzem

Calzem is the active form of vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes.

Other names for this medication:
Alfacalcirol, Arcium, Bonestat, Bonetuf, Calbec, Calbory, Calcibest, Calcimet, Calcirol, Calcitriol, Calcor, Calosto, Caltive, Calvical, Cholical, Citroj, Kurecal, Lctrol, Minroset, Netxod, Osteobel, Ritoca, Rockbon, Solbiocal, Sunmic, Tobalt, Vitalpha

Similar Products:
Adalat, Acticin, Zofran, Amoxil, Lopressor, Risperdal

Also known as: Calcitriol

Description

Generic Calzem is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calzem are intestine and bone. Generic Calzem receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calzem may also act on the kidney and the parathyroid glands. Generic Calzem is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calzem has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calzem, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calzem in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calzem produces other independent beneficial effects. Calzem is also known as Calcitriol. Generic Calzem treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calzem is Calcitriol. Brand name of Generic Calzem is Calzem.

Dosage

Generic Calzem is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calzem suddenly.

Overdose

If you overdose Generic Calzem and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calzem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Calzem if you are allergic to Generic Calzem components. Do not take Generic Calzem if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Calzem if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Calzem taking suddenly.

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