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Biokalm (Lorazepam)

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This medication is used to treat anxiety. Lorazepam belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. This drug works by enhancing the effects of a certain natural chemical in the body (GABA). Biokalm may also be used to treat: Symptoms from Alcohol Withdrawal, Mania associated with Bipolar Disorder, Adjunct Treatment, Muscle Spasm, Chronic Trouble Sleeping, A Feeling of Restlessness with Inability to Sit Still, Nausea and Vomiting caused by Cancer Drugs, Prevent Nausea and Vomiting from Cancer Chemotherapy, Psychosis caused by Sudden Alcohol Withdrawal.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Dostinex, Albenza, Pamelor, Motrin, Benemid, Minipress

Also known as: Lorazepam


Biokalm, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or intravenous routes of administration.

Biokalm is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Biokalm affects chemicals in the brain that may become unbalanced and cause anxiety. Biokalm is used to treat anxiety disorders.

Biokalm may be habit-forming and should be used only by the person it was prescribed for. Biokalm should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.


Take Biokalm exactly as it was prescribed for you. Follow all directions on your prescription label. Never use Biokalm in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Lorazepam may be habit-forming. Never share Biokalm with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away Biokalm is against the law. Biokalm should be used for only a short time. Do not take this medicine for longer than your doctor recommends.

Do not stop using Biokalm suddenly or you could have unpleasant withdrawal symptoms, including a seizure (convulsions). Ask your doctor how to safely stop using this medicine. Call your doctor if this medicine seems to stop working as well in treating your anxiety symptoms.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Biokalm can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biokalm is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biokalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Biokalm can interact with several other medications. It can also interact with certain supplements and foods.

Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

Biokalm and other medications

Below is a list of medications that can interact with Biokalm. This list doesn’t contain all drugs that may interact with Biokalm.

Before taking Biokalm, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.


Taking opioids with Biokalm can cause dangerous side effects. These include excessive drowsiness, breathing problems, respiratory failure, and coma.

Examples of these drugs include:

  • morphine (Astramorph PF, Kadian, MS Contin, and others)
  • oxycodone (Percocet, Roxicet, Oxycontin, and others)
  • hydrocodone (Zohydro ER, Hysingla ER)
  • methadone (Dolophine, Methadose)
  • fentanyl (Abstral, Duragesic, and others)
Opioids should only be used with Biokalm when there are no other treatment alternatives.

Sedative drugs

Taking sedative drugs with Biokalm can cause excessive drowsiness and breathing problems. Examples of sedative drugs include:

  • anticonvulsant medications such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), phenytoin (Dilantin, Phenytek), and topiramate (Qudexy XR, Topamax, Trokendi XR)
  • antihistamines such as diphenhydramine (Benadryl), cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton and others), and doxylamine (Unisom and others) — also found in over-the-counter and combination products
  • antipsychotic drugs such as clozapine (Clozaril, Fazaclo ODT), haloperidol (Haldol), quetiapine (Seroquel), and risperidone (Risperdal)
  • anxiety drugs such as buspirone (Buspar)
  • barbiturates such as phenobarbital
  • other benzodiazepines such as alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and midazolam

Taking Biokalm with probenecid, a drug that can be used to treat gout, can increase the levels of Biokalm in your body. This can increase your risk of Biokalm side effects. For people who take probenecid and Biokalm together, the Biokalm dosage needs to be reduced by half.

Valproic acid

Taking Biokalm with valproic acid (Depakene, Depakote), a drug used to treat seizures and other conditions, can increase the levels of Biokalm in your body. This can increase your risk of Biokalm side effects.

For people who take valproic acid and Biokalm together, the Biokalm dosage needs to be reduced by half.

Biokalm and Zoloft

Zoloft (sertraline) can make some people feel tired or drowsy. Biokalm can also cause drowsiness. Taking these medications together may cause you to feel even more tired or drowsy.

Biokalm and Ambien

Biokalm and Ambien (zolpidem) shouldn’t be taken together. Both medications are used to help promote sleep. If taken together, they can cause excessive sleepiness and sedation.

Taking this combination of medications can also increase the risk of odd behaviors such as sleep-driving (trying to drive while asleep).

Biokalm and Tylenol

There are no known interactions between Biokalm and Tylenol (acetaminophen).

Biokalm and herbs and supplements

Taking Biokalm with herbs or supplements that have sedative effects can cause excessive drowsiness and breathing problems. Examples of sedative herbs and supplements that can cause these effects include:

  • chamomile
  • kava
  • lavender
  • melatonin
  • valerian
Biokalm and marijuana

Marijuana shouldn’t be used with Biokalm. Using marijuana with Biokalm can cause excessive drowsiness or sedation.

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