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Avidal (Metronidazole)

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Avidal is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Amebidal, Amotrex, Anamet, Anegyn, Collazole, Corsagyl, Dazotron, Deflamon, Deprocid, Elyzol, Etron, Filmet, Fladystin, Flagemed, Flagenase, Gynotran, Klion, Metrodal, Metronidazole, Metrosa, Metrosil, Metrovax, Missilor, Monizole, Negazole, Nidazol, Otrozol, Patryl, Perilox, Protozol, Rhodogil, Robaz, Rosaced, Rosalox, Rosasol, Rosazol, Rovamet, Rozamet, Stomorgyl, Taremis, Trichozole, Tricofin, Varizil, Vertisal, Wingyl, Zobacide

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Also known as: Metronidazole


Generic Avidal is created by pharmacy specialists to struggle with dangerous infections spread by bacteria (it can be protozoa or anaerobic bacteria). Target of Generic Avidal is to control, ward off and terminate bacteria. Generic Avidal acts as an anti-infection remedy. Generic Avidal operates by killing bacteria which spreads by infection. Avidal is also known as Metronidazole. Generic Avidal and other antibiotics don"t treat viral infections (flu, cold and other). Generic Avidal also does not help with vaginal yeast infection. Generic name of Generic Avidal is Metronidazole. Brand names of Generic Avidal are Protostat, Avidal, Avidal ER, Avidal 375.


In the Female. One-day treatment – two grams of Avidal, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


Single oral doses of Avidal, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Avidal has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Avidal overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avidal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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This prospective study investigates the use of intraoperative fluoroscopy in hallux valgus surgery. Parent-reported quality of preventive care for children at-risk for developmental delay. An isolated rat brain preparation was used to avoid the contribution of peripheral reactions. How the musical tempo affects the performance of heart rate variability (HRV) was studied in this work. Items assessed knowledge of and opinions and adherence to asthma guidelines in general and the GEMA in particular. Our results illustrate how cells deploy the danger receptor galectin 8 to combat infection by monitoring endosomal and lysosomal integrity on the basis of the specific lack of complex carbohydrates in the cytosol. Effects of childhood hearing loss on organization of semantic memory: typicality and relatedness. Adverse effects of phenobarbital on corticosteroid metabolism in patients with bronchial asthma.

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In the present study, a novel colorimetric indicator for a vast variety of G-quadruplex was designed and synthesized on the basis of thiazole orange and isaindigotone skeleton. Nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are originally characterized as transcription factors regulating many target genes. Additionally, there also exist gender-specific behavioural patterns, which influence the risk of cancer as well as the acceptance of certain arrangements for prevention, screening, therapy and follow-up of colorectal cancer. Thus, three types of hospitals will be defined for stroke care: reference stroke hospital, hospital with stroke unit, hospital with stroke team. Total mesocolic excision may improve survival in patients with colon cancer. Incubation of Raji cells with L-744,832 led to up-regulation of CD20 at mRNA and protein levels. A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems.

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It can be idiopathic, parainfectious, or paraneoplastic with tumours of the neural crest. albicans at 2 tertiary care hospitals during the period 1995-2005. Our continuous observations over the last 12 years confirm that chimpanzees, when sick, may ingest plant material that are not generally eaten, supporting the existence of self-medication among great apes. This research explores the effect of emotional states on visual detection. A key issue that emerges is that climate-induced hybridisations in insects are much more widespread than anticipated and that rising temperatures and increased anthropogenic disturbances are accelerating the process of species mixing. Manual point placement for vertebral morphometry is time-consuming and imprecise.

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Zirconia Implants in Esthetic Areas: 4-Year Follow-Up Evaluation Study. The transmission of the 6/18 translocation in this family is discussed. The effect of bacteriophage induction on the repair ability of Escherichia coli 15 TAU. The resulting steady-state motion is detected in real time via an ultra fast ultrasound system using classical, one-dimensional (1-D) ultrasound speckle correlation for motion estimation. Raman spectra and conformational properties of ribosomes during various stages of disassembly. Foot-and-mouth disease control in the Songwe Valley, Malawi--a review.

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Blended learning is effective and well evaluated by dental students and can be implemented in undergraduate curriculum for teaching oral radiology. Multivariate linear regressions assessed the associations between each adverse experience and an index of child well-being with and without the impact of other events. Recent work adds to this paradox by questioning the role of CENP-A as a unique centromeric mark and highlighting the assembly of a functional kinetochore in the absence of CENP-A. Both diagnostic techniques and characteristics of chronic rhinosinusitis vary in a broad range depending on the standards adopted in different countries. As seen with previous cytokine treatment, long-term response is a key clinical outcome. The reaction can be carried out in a drop of water directly on the surface without photoinitiator, and any disulfide side products were easily washed away after the functionalization process. Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) colonization and infection in intravenous and inhalational opiate drug abusers. Instances of incorrect approach to the study of higher nervous activity types. cuniculi transporters can transport ATP, and three of them are expressed on the surface of the parasite when it is living inside host cells. Cytoplasmic extensions were seen linking the cells on adjacent microspheres.

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Release Studies on Ciprofloxacin Loaded Non-ionic Surfactant Vesicles. Accurate pre operative assessment and safe surgery offers cure to all patients with primary hyperparathyroidism. Stray capacitance across the oil gap was measured after each experiment and its admittance subtracted from the admittance of the fiber and oil gap. Combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A multicentre trial. The results suggest that visual processing of spatial frequencies comprises relatively separate subsystems with different spatiotemporal response characteristics. In alloxan-diabetic rabbits the increase in heart rate after insulin was not abolished by autonomic blockade.

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When separate models were developed for postcode clusters, they demonstrated that the link between outlet density and violence was significant in all neighborhood types, but the specific relationships varied substantially. Moreover, recent studies have also begun to document the importance of epigenetic landscape evolution of the KSHV viral genome during latency and reactivation. These genomes are extremely vulnerable to insult and mutations in mitochondrial DNA (mtDNA) have been linked to several neurodegenerative diseases, as well as the normal process of aging. The one-step pyrolysis process at 750 degrees C under nitrogen atmosphere results in the simultaneous decomposition of the chitosan nanospheres to HCNs and the adsorbed metal salt complex to metallic nanoparticles. The new chromogenic medium showed excellent performance for the detection of Group B streptococci from clinical samples. Nevertheless, catastrophic cause of chest pain such as ACS, AD, PE, esophageal perforation, and pericarditis must be considered in the differential diagnosis.

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In Saccharomyces cerevisiae, basic amino acids accumulate preferentially into vacuoles but acidic amino acids are almost excluded from them. These patients quite frequently consume androgenic anabolic steroids, human growth hormone and other drugs or substances which are believed to accelerate muscle gain. The present study shows that veA homologues are broadly distributed in fungi, particularly in Ascomycetes. Surgical pharyngotomy with a trans-hyoid approach provides good access to the lesions. We sought to understand how AEDs are used and socially constructed among young people. Ultrasonic tissue characterization of prostate biopsy tissues by ultrasound speed microscope. Importantly, the novel advances in this rather new field of nanoscience are organized into a coherent overview aimed to rationally describe the different strategies and improvements in the exploitation of colloidal nanoparticle assembly for SERS application to real problems.

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Pharmacokinetics of alteplase in the treatment of ischaemic stroke. We used the most rigorous definition of abstinence available in each trial. Food intake and nutrient adequacy of rural population of Andhra Pradesh, India. In 2004, data were collected for approximately 371,000 discharges. This work primarily aims to fabricate and use two photon polymerization (2PP) microstructures capable of being optically manipulated into any arbitrary orientation. Proteinuria was present on day 1, increasing to 20 g/L after 3 days. PEITC is of considerable interest as a potential chemopreventive/chemotherapeutic agent, and in this work, we have investigated the effects of PEITC on human breast cancer cell lines. Studies adopting HAIC as a neoadjuvant bridging therapy for hepatic resection for CRLM were included. Local application of NGF lodine pain pill can promote nerve regeneration and sensory recovery of grafted skin. the gastrointestinal loss and consequent depletion of the long-lived, recirculating population of lymphocytes from the peripheral lymphocyte pool.

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In our study, the average pH for individuals without symptomatic reflux or eustachian tube dysfunction was 7.03. The intervals from primary renal tumor resection to recognition of metastases in the pancreas varied from 6-17 years. We prove consistency of the proposed method, and describe an extension to partially linear models. Together, our results identify a peptide derived from the proregion of falcipain-2 that blocks late-stage malaria parasite development in RBCs, suggesting the development of peptide and peptidometric drugs against the human malaria parasite. Probiotic Escherichia coli Nissle 1917 versus placebo for treating diarrhea of greater than 4 days duration in infants and toddlers. Recent vs Conventional Methods of Caries Removal: A Comparative in vivo Study in Pediatric Patients. mediterranei CGMCC 1.2087, consisting of one chromosome and three megaplasmids. A three-dimensional model--based on the student (local or international), the teacher (local or international), and the curriculum (local, imported, or international)-offers a range of perspectives for international medical education. Recent studies suggest epileptiform transients in the first 6-8 hours are predictive of outcome. In contrast, characters related to song pulse properties (PL, CN and carrier FRE) mapped to the region of chromosome 2 near the candidate gene fruitless, identifying these genes as suitable loci for further investigations.

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The scene times and transport times were compared before (from January 2003 to December 2005) and after (from January 2006 to April 2008) implementation of the PH ECG. Furthermore, the neuroadaptations known to be associated with sensitization may be somewhat distinct from those that lead to changes in impulsive choice. The sand samples were obtained from the play area and the sandbox of a day care centre and examined for the presence of FC and Toxocara species, the common roundworm of dogs and cats. Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. Adhesion formation between the flexor tendon and its surrounding fibro-osseous sheath results in a decreased postoperative range of motion in the hand.

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Neutrophil chemotaxis defect in IgA deficiency evaluated by migration agarose method. Frequency of ischemic disease was significantly higher in the group treated with COX-2 inhibitors than in the non-selective NSAID treated group or in patients without NSAID treatment. On the basis of their unique spectrum of activities, several factors are approved for clinical use in various indications while others are under investigation in the clinic either alone or as combination therapy. Anthoxanthum has become locally adapted to differences in soil Al toxicity, which have developed there due to soil acidification from long-term experimental fertilizer treatments. Uroperitoneum in cattle: Ultrasonographic findings, diagnosis and treatment. Furthermore, prolonged sitting can result in both reduced spinal height (SH) and lumbar range of motion (LROM). The main focus of this chapter is technical issues although statistical issues are also covered to certain extent. To understand the associations between symptoms and echocardiographic covariates, a logistic regression analysis was performed adjusted for age and gender. Honokiol induces cell cycle arrest and apoptosis in human gastric carcinoma MGC-803 cell line. The environmental sustainability of the oil adsorbed nanobiocomposite is also demonstrated here through its conversion into a bi-functional graphitic nanocarbon material via heat indapamide review treatment.

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Oligosymptomatic thyrotoxic crisis and its treatment by plasmapheresis. Patients underwent laparoscopic cholecystectomy, appendectomy, splenectomy, colectomy and Nissen fundoplication. The presence of seven genes encoding NCX homologs may provide teleosts with the functional specialization analogous to the alternate splicing strategy seen with the three NCX mammalian homologs. Suppositories containing 25 mg of indomethacin were made by the fusion method with theobroma oil, esterified fatty acids (C10-C18), and polyethylene glycol 1000. A visual search test using the same stimulus material (but not requiring a verbal response) and an oral articulation test were also given. The safety profile of Gd-BOPTA is similar to Gd-DTPA whats the max dose of buspar in patients and volunteers. The cluster solution from this binary data indicated similarities for five populations that differed from those suggested by morphometrics. This may be due to (1) more extensive donor and recipient preparation and evaluation for surgery, (2) improvement of surgical technique with increasing experience in donor and recipient, and (3) more refined diagnosis and treatment of urologic and infectious complications. Plastidial Glycolytic Glyceraldehyde-3-Phosphate Dehydrogenase Is an Important Determinant in the Carbon and Nitrogen Metabolism of Heterotrophic Cells in Arabidopsis.

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Mortality and the self-controlled case series method: letter to the editor. Here, we will outline the key pathophysiologic differences between the chronic and the blast phase, the mechanisms that contribute to these differences, and how these might be therapeutically targeted in patients. Dacomitinib (PF-00299804) is an oral, irreversible, small molecule inhibitor of human epidermal growth factor receptor-1, -2, and -4 tyrosine kinases. Mesenchymal stem cells (MSC) are arising as a potent therapeutic tool in transplantation due to their regenerative and immunomodulatory properties. Follow-up survival studies in patients with acute type B aortic dissection have been restricted to a small number of patients in single centers. The expression patterns of all identified Sox genes were examined from gastrulation through early organogenesis (embryonic day 4-14), with particular emphasis on the neural crest, a vertebrate innovation.

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While the main cause(s) of IBD remain unknown, a number of interventional and preventive strategies have been proposed for use against CD and UC. We investigated the possible role of endogenous hydrogen sulfide (H(2)S) of cerebrospinal fluid (CSF) in predicting CNSL. To test the effect of insulin treatment on the pharmacokinetics of metformin in rats with diabetes mellitus induced by alloxan (DMIA rats). Now, apparent misalignment increased the more the 3-D blocks were perceived as receding in depth. To analyze the degree and pattern of influence of magnetic resonance imaging (MRI) on staging according to the 6th edition of the American Joint Committee on Cancer staging system compared with computed tomography (CT). Outcome measures were stroke (ischemic and hemorrhagic), myocardial infarction, venous thromboembolism, and major systemic bleeding (i.e., requiring transfusion) up to 4 weeks after the procedure among patients who had medications continued versus temporarily discontinued. Further, molecular sensors of intracellular calcium release aid in antigen mediated inhibition of apoptosis.

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