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Astrim (Trimethoprim)

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Astrim is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Astrim, Avlotrin, Bactelan, Bactipront, Baktimol, Biseptrin, Chemitrim, Cotrim, Cotrix, Diseptyl, Ditrim, Eliprim, Escoprim, Lagatrim, Octrim, Ottoprim, Primazole, Primotren, Septrin, Sigaprim, Sitrim, Spectrem, Sulbron, Sulfatalpin, Sultrim, Triforam, Trimetoger, Trimezol, Trimoxsul, Zaxol, Zoltrim

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Also known as: Trimethoprim


Generic Astrim is taken to fight against ear infections, urinary tract infections, bronchitis, traveler's diarrhea, Pneumocystis carinii pneumonia. Generic Astrim works by killing or slowing the growth of sensitive bacteria. Generic Astrim can't be given to children younger than 2 months old. Astrim is also known as Co-trimoxazole, Septra, Ciplin, Septrin. Generic names of Generic Astrim are Sulfamethoxazole, Trimethoprim. Brand names of Generic Astrim are Astrim, Astrim DS, Septra, Septra DS, Sulfatrim Pediatric.


Shake this medication well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection.


If you overdose Generic Astrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Astrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Astrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Astrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Astrim is contraindicated in pediatric patients less than 2 months of age. Astrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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