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Alpra (Alprazolam)

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Alpra is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpra is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpra may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Almee, Alparazole, Alpkair, Alprine, Alprop, Alsert, Altalin, Altrex, Alwe, Alzoft, Ambulax, Betapax, Cooltime, Depsolam, Depwell, Emlol, Endep, Eurolam, Pacyl, Tenolam, Tenrid, Tensyl, Texidep, Unixl, Zallpam, Zedel, Ziety, Zolin

Similar Products:
Lipitor, Sporanox, Minocin, Hydrea, Dilantin, Cordarone

Also known as: Alprazolam


Alpra is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpra is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpra if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpra or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpra. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alpra with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alpra. Ask your doctor how to avoid withdrawal symptoms when you stop using Alpra.

Keep track of the amount of medicine used from each new bottle. Alpra is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


If you have been prescribed Alpra for medical reasons, the best way to avoid a Alpra overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpra consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alpra, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alpra is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Enterostatin inhibition of dietary fat intake is dependent on CCK-A receptors. A study was conducted to assess the effects of the intervention on inequities in knowledge, access, ownership and use of ITNs. The purpose of this study was to determine under laboratory conditions over a period of 311 days if infection with the nematode Anguillicola crassus induces stress in European eels (Anguilla anguilla), and stimulates the endocrine stress axis as measured by serum cortisol levels. These data indicate that the therapeutic potential of DOR agonists for alcohol abuse is through a selective action at the DOR-1 form of the receptor. A collection of 186 heterotrophic bacteria, isolated directly from a continuous-upflow fixed-bed reactor for the denitrification of drinking water, in which poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) granules acted as biofilm carrier, carbon source and electron donor, was studied with regard to taxonomic affiliation and degradation and denitrification characteristics. We showed the inhibitory effect of oleic and palmitoleic acids (OA and POA) on this trans10, cis12 (10t, 12c)-CLA induced cytotoxic activity. The structures were mainly deduced from extensive 1D and 2D NMR spectroscopy and mass spectrometry.

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This is the first time that DARC has been used to determine apoptotic effects in the inner nuclear layer. Corticosterone and insulin interact to regulate glucose and triglyceride levels during stress in a bird. In an attempt to elucidate the current state of the science of BFRs, we review the consumer demand for BFRs (mainly in Japan), the characteristics of waste flame-retarded products, sources of emission, environmental behavior, routes of exposure of humans, temporal trends, and thermal-breakdown products of BFRs. Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. Differences between h-index measures from different bibliographic sources and search engines. A population was produced by crossing the stem rust susceptible line RL6071 with Webster. CDK5 is present in sea urchin and starfish eggs and embryos and can interact with p35, cyclin E and cyclin B3.

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Hepatic resection is advocated and tailored to pathological T stage. General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem. Digital fluoroscopic video assessment of glenohumeral migration: Static vs. Effects of 8-methoxypsoralen (8-MOP) and UVA on human lymphocytes. The combined results of this trial and the complementary trial among normal birthweight neonates have now shown that, overall, it would not be beneficial to implement a neonatal vitamin A supplementation policy in Guinea-Bissau. No problems were associated with administration of surfactant, and no acute side effects were detected. Evaluation of transgenic Bt corn for resistance to the Asian corn borer (Lepidoptera: Pyralidae). Fecal virus shedding persisting for at least 7 days was detected by both reverse transcription (RT)-PCR and antigen-enzyme-linked immunosorbent assay (antigen-ELISA) in both TC-PEC and WT-PEC orally inoculated pigs but not in mock-inoculated pigs. To understand how Expanded regulates Hippo pathway activity, we used affinity chromatography and mass spectrometry to identify Expanded-binding proteins. Based on this case and a review of current literature, in addition to therapeutic lifestyle change, red yeast rice may be a useful alternative treatment for primary hyperlipidemia in patients with low cardiac risk and who refuse to take any lipid-lowering prescription medication or who maybe be statin intolerant.However, primary care physicians must be aware of the potential side effects of taking red yeast rice.

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Effects of neonatal hypoxia/ischemia on ganglioside expression in the rat hippocampus. USE of pseudomonas stutzeri and candida utilis in the improvement of the conditions of artemia culture and protection against pathogens. Assessment of the antiviral activities of these novel compounds against a broad panel of viruses in different cell cultures revealed that only the thiazole derivatives belonging to the benzisothiazol-3(2H)-one-1,1-dioxide series are the active ones. Influence of the BGE composition on analyte response in CD-mediated NACE-MS. A total of 28 kilobases (kb) of contiguous DNA surrounding the CDC24 and PYK1 genes was isolated, and a restriction map was determined. These results suggest that LD may constitute a risk factor for PPA, providing additional clues concerning the determinants for the selective vulnerability of the language network in this syndrome. We developed a MIF DNA vaccine by introducing oligonucleotides encoding a tetanus toxoid (TTX) Th cell epitope into the complementary DNA sequence of murine MIF. Together, these observations expand upon the nature of PACR1-mediated transactivation and identify TrkA-Rit signaling as a key contributor to PACAP-dependent neuronal differentiation. Determination of palladium in human urine by high-performance liquid chromatography and ultraviolet detection after ultraviolet photolysis and selective solid-phase extraction.

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Moreover, on the basis of the distribution of T1, the microporosity fraction can be computed, as well as several voxel-average porosities. In this work, the behaviour of the intramyometrial pressure, registered in the wall of the myometrium of the human isolated nonpregnant uterus, has been followed up. During the past five years, a number of reports have described the ultrasound features of intracranial infection, including echogenic sulci, extra-axial fluid collections, ventricular enlargement, calcifications, abnormal parenchymal echogenicity, abscess formation, cystic degeneration of the brain parenchyma, intraventricular echogenicity, ventricular septations and irregularity and prominence of the ventricular walls. Course of disease depends on the degree of lesion, low-grade lesion will improve earlier and prognosis of motor recovery is good. This unit behavior accounts for an initial step on the unfolding pathway, a final step in refolding, and a number of other structural, functional and evolutionary properties. Atmospheric moisture effects on the testing rate and cementation seating load following resin-strengthening of a soda lime glass analogue for dental porcelain. Samples of paraffin-embedded tumour tissue from 43 children with unilateral retinoblastoma were collected to investigate the presence of HPV DNA using polymerase chain reaction (PCR) and dot blot hybridization. These data highlight the extreme plasticity of the MHC class I gene system. Immunofluorescence and immunoperoxidase analyses performed on normal human fetal and adult tissue sections have demonstrated that these antigens are expressed by different cell types and domains of the nephron. As aromatase-deficient mice, which are deficient in estrogens, reportedly have reduced blood pressure, the aromatase gene (CYP19A1) is thought to be a susceptibility gene for essential hypertension (EH).

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Total hip arthroplasty after previous support proximal femoral osteotomy. In vivo, HDAC3 forms a stable complex with the SMRT corepressor. Participants were receptive of colocated pharmacist services, and various barriers and facilitators to integration were identified. Quantitation of proteinuria by the use of protein-to-creatinine ratios in single urine samples. This study provides insight into antismoking socialization efforts in rural African American families and confirms that African American families are actively engaged in keeping their children from smoking. We have shown that these multiplex arrays were employed to screen markers potentially involved in the disease, among a wide spectrum of proteins, without a preliminary robust biological hypothesis. Also, the molecular interaction of rhodamines in normal solvents (isotropic hosts) was studied using visible spectroscopy for comparison. Metabolic syndrome was defined according to the International Diabetes Federation criteria.

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This case adds to the increasing incidence of treatment failures with ciprofloxacin in typhoid fever caused by typhoid salmonellae with reduced susceptibility to ciprofloxacin. Group by condition interactions in the putamen, caudate, and right inferior frontal gyrus were observed. The human immunodeficiency virus (HIV) and the acquired immunodeficiency syndrome induce account for over 40 million deaths in the past 20 years. A description of one of the most comprehensive and established training programmes in the UK is presented. By using this method effective combinations of stabilizers for urate oxidase were found, and possible reasons of their stabilizing influence on the enzyme are discussed. Consistent with this hypothesis, in vitro experiments performed with pure pyruvate kinase and phosphoglycerate kinase showed that oxidation of these proteins can be prevented by magnesium and increased by the presence of ATP. In pure silica sand and coarse sandy loam, nematodes introduced 14 cm below the soil surface were able to infect wax moth pupae located between 4 and 24 cm.

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Analysis was performed on a high-molecular fraction with fibrinogen antigenicity present in Liquid Human Plasma. Reproductive time lost through marital dissolution in metropolitan Latin America. Nine different Ag-Sn particles including standard Sn, SnO and SnO2 were evaluated by X-ray Photoelectron Spectroscopy (XPS). The effect of numbers of predators depends on whether predation intensity also changes. He was diagnosed with temporal arteritis and treated with systemic steroids. There was only little reliable evidence for which are the most effective interventions for maintaining or recovering health of peri-implant soft tissues. The polyacrylamide gel is proposed here as a phantom material for NMR imaging. Patients were treated with accelerated radiotherapy with a total tumour-dose depending on normal tissue dose constraints.

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During long (but not short) days, the birds responded in line with theoretical predictions by increasing their reserves in response to interruption and reducing them in response to predation. This paper should give an overview about the radiologic findings and possible differential diagnosis of diverse pulmonary fungal infections in CT. The unique feature of female development was the occurrence of large vaginal primordial cells. The significant protective effect of exclusive breast feeding against pneumonia in this cohort and the evident role of recurrent wheezing as risk factor for pneumonia during the first year of life support the implementation or reinforcement of public policies encouraging exclusive breastfeeding and an adequate management of wheezing since the first months of life. An antenatally diagnosed case of a left congenital diaphragmatic hernia is reported. They are also localized in a differential pattern in normal, non-sun-exposed, adult skin, a finding that supports the supposition that these enzymes might have different functions in the skin, but relatively little is known about their functions in the skin. Previously, we reported the existence of a splice variant, GRM3Delta4, which has an exon 4 deletion and encodes a truncated form of the receptor that is expressed in brain. Gefitinib in combination with capecitabine as second-line therapy in patients with advanced colorectal cancer (aCRC): a phase I/II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

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In this study, we reviewed retrospectively 36,971 autopsy reports recorded by the Mortuary Section of the Forensic Medicine Council of Istanbul between January 1, 1998 and December 31, 2007. Computerised ST segment analysis was used to compare the frequency of ischaemia occurring in electrocardiographic leads II, V5, CS5 and CB5. However, procedural simplification in oral implantology is not synonymous to poor patient preparation. Moderator role of perfectionism between negative life events and depressive symptoms among Turkish youth. We present a 20-year-old man who was operated upon for a skull cavernoma in the right frontal area and developed a new lesion 3 years later in the right occipital region. Non-adherence to tuberculosis treatment: a study on perceptions and knowledge of the disease and evaluation of health services from the patient perspective. Final visual acuity was R.E.: 6/15 (20/50), and L.E.: 6/6 (20/20).

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These vaccines stimulated elevated Ag-specific Ab-forming cells and mixed Th cell responses, with Th17 cells markedly enhanced by i.m. Performance of calcium deficient hydroxyapatite-polyglycolic acid composites: an in vitro study. Kinetics of IFNg secretion with different antigens showed a plateau after bactrim ds dosage in cats 24h culture. Detection of immunoglobulin G human leukocyte antigen-specific alloantibodies in renal transplant patients using single-antigen-beads is compromised by the presence of immunoglobulin M human leukocyte antigen-specific alloantibodies. The selective use of rapid aneuploidy screening in prenatal diagnosis. In order to provide a reliable nociceptive stimulus, two devices have been constructed, one that provides a threshold reading for a ramped thermal stimulus of the pinna of the ear and another that measures a threshold reading for a pressure stimulus to the foreleg. A dynamic river water quality model was applied to simulate the river hydraulics and water quality variations during the event. Mouse B16 melanoma sublines were selected sequentially for their abilities to colonize brain meninges and leptomeninges of C57BL/6 mice. A periplasmic expression system was designed for the heterologous expression of LbpA, which enabled the investigation of its binding activity in the absence of lactoferrin-binding protein B (LbpB).

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The current model proposes that phosphatidic acid plays a biophysical role, generating a negative curvature and thus promoting fusion of secretory vesicles with the plasma membrane. To address this issue, we developed a novel nanoparticle delivery method that differs from the nanoparticles reported to date because its core was composed of cross-linked dextran glassy nanoparticles which had pH in endosome-responsive environment and the protein was loaded in the core of cross-linked dextran glassy nanoparticles. Moreover, the secondary antifungal prophylaxis can provide active roles for patients scheduled for chemotherapy and/or HSCT. Betaine, an osmoprotectant and methyl donor, is a component of sweat that may be lost from the body in significant amounts. Carbon sequestration potential of soils in southeast Germany derived from stable soil organic carbon saturation. Relationship of gestational age, severity of hemolytic diseases, and birth asphyxia to idiopathic respiratory distress syndrome and survival. To study the features of blood supply and results of transarterial infusion and embolization in spinal metastases.

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Moreover, different stimulation frequencies may elicit either crying or anxiety but not both. Disease outcome in newly diagnosed patients with destructive pulmonary tuberculosis (based on dispensary observations). Of the seven cases reported, five experienced an improvement in visual function in their preferred retinal locus with eccentric refraction. These are consistent with experimental observations of chain formation and two-dimensional self-assembly in bulk nematics and smectic-C films. The v-sis oncogene and its cellular homolog c-sis encode chain B of platelet-derived growth factor. Analyses of barley how to use albendazole 400 mg tablet spike mutant waxes identify alkenes, cyclopropanes and internally branched alkanes with dominating isomers at carbon 9. At the site of bulge development, vesicular mesosomelike structures appeared in the cytoplasm, the peptidoglycan layer facing them became faint, and the outer membrane protruded to form blebs. Mathematical properties of some measures of evolutionary distance. De novo malignancies following liver transplantation: results from a multicentric study in central and southern Italy, 1990-2008.

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Low-grade myxofibrosarcoma often relentlessly recurs after surgical resection, with an unusual infiltrative growth pattern and sometimes without a discrete tumor nodule at pathologic examination. Although the vacant lower axial site in the rhenium complex is the site most easily attacked by Y, transition states for X leaving from the site cis to the attack have quite low energy barriers. Microsatellite analyses showed evidence of association at two contiguous markers, both located at the same genetic distance and spanning approximately 11 known genes. These results provide the strongest evidence to date that historical climate patterns can drive the rapid evolution of avian migration in natural populations, and they suggest a general mechanism for the repeated evolution of migration within and across bird lineages. Reporting standards for uterine artery embolization for the treatment of uterine leiomyomata. This suggests that the physiological mechanism(s) underlying chronic sleep debt undergo long-term (days/weeks) accommodative/adaptive changes. Association between lipoprotein(a) levels, apo(a) isoforms and family history of premature CAD in young Asian Indians. Because of their compromised immune system, transplant patients have a high risk for visceral involvement of VZV infections, which are a life-threatening emergency.

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Identification and organization of chloroplastic and cytosolic L-myo-inositol 1-phosphate synthase coding paxil 60 mg pill gene(s) in Oryza sativa: comparison with the wild halophytic rice, Porteresia coarctata. In this work, hologram quantitative structure-activity relationship (HQSAR), comparative molecular field analysis (CoMFA), and comparative molecular similarity indices analysis (CoMSIA) methods were employed to develop 2D- and 3D-QSAR models for 54 anti-tumor RAs. Pleiotropy in the melanocortin system: expression levels of this system are associated with melanogenesis and pigmentation in the tawny owl (Strix aluco). This treatment method compares well with previous published series and is to be recommended for this group of difficult fractures. Taken together, the strategy to make combody could be widely adopted to increase the avidity of Ab fragment for further application. Attention-deficit/hyperactivity disorder (ADHD) is a psychiatric disorder characterized by inattention, impulsivity, and overactivity that begins in childhood. Hantaviruses cause changes in the function of infected endothelial cells that normally regulate fluid barrier functions. Although increased flux of glucose through the polyol pathway leads to diabetic lesions in both the lenses and nerve, the mechanisms may be different.

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Increased disorderliness of hormone secretion is a hallmark of pituitary adenomas, indicating functional subsystem autonomy. Patients with no preceding clinical diagnosis of BD, despite previous manic, hypomanic or mixed phases and treatment in psychiatric care, were classified as undiagnosed. Murine models of Candida gastrointestinal colonization and dissemination. Prolonged exposure to N2O leads to megaloblastic anemia in humans and to loss of methionine synthase activity in vertebrates. Furthermore, NS1209 was safe and well tolerated at the given doses with a safety profile similar to placebo. Increased recombination and selection in barley populations carrying a male sterility factor. Its major advantages are: simplicity, low cost and the synchronization of pulse generation with the arterial roller. To support the discussion of the DSM-III as well as to facilitate its clinical use, its diagnostic categories are contrasted with the diagnostic categories of the ICD-9.

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The cusped interferogram created by superposition of evoluting two initial diffraction patterns, created during successive damage steps, forms caustics corresponding to hyperbolic umbilic catastrophes. The technique involved color Doppler digital images of transpyloric flow in which the 3D position and orientation of the images were known by using a magnetic location system. Portal vein ligation (PVL) is increasingly employed prior to major hepatectomy in order to enhance the volume of the future liver remnant (FLR) and to avoid post-hepatectomy liver failure. Somatostatin is known to inhibit the actions of inhibitory neurotransmitters in the pylorus and may explain the development of pylorospasm, which is believed to be important in the development of pyloric tumours. This also sheds light on the importance of mass media as a means of synchronization between the topmost and bottommost classes. Specific extranodal sinoatrial muscle cells in the crista terminalis. The use medication class of atarax of finite slits for obtaining the LSF is analyzed theoretically. This requirement has probably favored the development and spread of specific microorganisms with particular physiological and metabolic processes. Treatment outcomes in rheumatoid arthritis (RA) have improved considerably with the use of biological therapies.

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