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Alpostin (Alprostadil)

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Alpostin injection is used to treat men who have erectile dysfunction (also called sexual impotence). Alpostin is used alone or with medical tests to help diagnose erectile dysfunction that may be caused by nerve or blood vessel problems in the penis.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Alpostin injection is used to treat certain heart, lung, and blood vessel problems in infants. It is used to temporarily keep the ductus arteriosus (blood vessel in the heart) open before having a surgery.

This medicine is to be given only by or under the supervision of your child's doctor.

This product is available in the following dosage forms:

  • Solution


Alpostin is produced in a liquid form and is administered by injecting it directly into the side of the penis. It is important to make sure that you understand how to do this properly. If you are unsure, consult your doctor or healthcare provider. For the purposes of injecting this medication, always choose a less visible blood vessel. After injecting the medication, apply pressure to the affected area with an alcohol swab for about 5 minutes to avoid bruising. The injection must not be administrated close to the surface of the skin, at the top or head of the penis or at the base of the penis near the scrotum or testes. According to the etiology of the erectile dysfunction, the initial dose may vary: - For vasculogenic or psychogenic erectile dysfunction, or for erectile dysfunction of mixed etiology, the starting dose is 2.5mcg. If there is no effect, you may increase the dose to 5mcg, followed by increments of 5–10mcg until the desired result (dose produces an erection for appropriate sexual intercourse and it doesn't last more than 1 hour). If there is still no response to the initial dose, you may give a second dose of 7.5mcg within one hour, followed by increments of 5–10mcg until the desired result is achieved. - For erectile disorders of neurogenic etiology, the recommended dose is 1.25mcg. You may increase the second dose to 2.5mcg, and the third dose to 5mcg, followed by increments of 5mcg until the desired result is achieved. The maximum dose is 60mcg per day. Allow a 24 hour interval between doses. Use Alpostin only as needed. Do not take a double dose of Alpostin.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately. The overdose of the medication may be followed by feeling light-headed, fainting, having a painful or prolonged erection lasting 4 hours or longer.


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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Alpostin if you are allergic to any of its components or to other prostaglandins. Do not take Alpostin if you have blood problems such as sickle cell anemia or sickle cell trait, leukemia. You should not be treated with Alpostin injection if you have penile implants. Do not take Alpostin if you have penile problems, e.g. a curved or deformed penis. Do not use Alpostin if you have multiple myeloma or other bone marrow problems. Do not take Alpostin if you take other medicines for the treatment of erectile problems. Consult your doctor or health care professional immediately if the erection lasts longer than 4 hours or if it becomes painful. Alpostin is not a protector from sexually transmitted diseases or pregnancy. Avoid having unprotected sex. Do not share drug needles. Do not drive or operate machinery while taking the medication. Avoid consuming alcohol as it may worsen the medication side effects. Alpostin does not protect you and your partner from sexually transmitted diseases and pregnancy. Alpostin is not for use in women, children or newborns.

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