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Alfatrim (Trimethoprim)

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Alfatrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

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Also known as: Trimethoprim


This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication should not be used in children less than 2 months of age due to the risk of serious side effects. This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.


Shake this medication well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection.


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Alfatrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Alfatrim is contraindicated in pediatric patients less than 2 months of age. Alfatrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Phylogenetic analyses mapped the LHS1/OSM5 duplication event to the base of the grass family. Full-term children born small or appropriate for gestational age might present transitory or permanent central hearing impairments, regardless of the presence of risk indicators. World Kidney Day on March 8th 2012 provides a chance to reflect on the success of kidney transplantation as a therapy for end stage kidney disease that surpasses dialysis treatments both for the quality and quantity of life that it provides and for its cost effectiveness. In the present study, we report chemically synthesized, multi-target gene interfering RNA structures based upon branched, tripodal interfering RNAs (termed T-tiRNAs). A structure activity relationship of the C-2 substituted ether analogs of 1,5-naphthyridine oxabicyclooctane-linked NBTIs are described. In this work, we present a unique ultra-high sensitivity photodetector technology with light sensitivity, signal amplification, light adaptation that shows signal transduction performance approaching those of the rods and cones in the mammalian retina. A multicolor time-resolved fluorescence aptasensor for the simultaneous detection of multiplex Staphylococcus aureus enterotoxins in the milk.

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Long-term antiviral treatment for recurrent hepatitis C after liver transplantation. Using an axisymmetric model, we found that the meridional and circumferential components of the resultant are different near the tether body and they converge to the value of membrane tension farther from the tether. Our case also emphasizes the difficulty to morphologically assess pathological response and the need for new tool to better select patients who should be resected. The results obtained so far show that the measurement of the subcapsular pressure is of particular significance in determining the extent of ischemic tubular damage, in early recognition of acute rejection and i assessing the effectiveness of immunosuppresive treatment for rejection. Little is known about the effects of non-MAOI antidepressants on cognitive functions, despite their wide application to ambulant patients. Lichenoid Reactions in Association with Tumor Necrosis Factor Alpha Inhibitors: A Review of the Literature and Addition tenormin ls 50 mg tablets of a Fourth Lichenoid Reaction. Knockdown of EIF3B expression significantly inhibited proliferation of U87 cells. Fast-Fourier-transform-based numerical simulations clearly demonstrate that the far-field images of the retrieved probe light can be flexibly modulated by applying different signal fields. We present a theory able to treat the DRL rigorously and provide results on the lasing spectra, internal fields, and output intensities of DRLs.

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This key transformation was accomplished with the aid of the molybdenum alkylidyne complex 7, which turned out to be compatible with the acid sensitive propargylic alcohol substituents as well as the terminal alkyne unit present in the cyclization precursor. This so called Vertico-SMI transfers the advantages of SMI nanoscaling to vital biological systems, and is shown to work consistently at different temperatures using both oil- and water-immersion objective lenses. Skin aging entails drastic changes in the extracellular dermal matrix (ECM) and dermal-epidermal junction (DEJ). Gender-specific correlations of plasminogen activator inhibitor-1 and tissue plasminogen activator levels with cardiovascular disease-related traits. Effect of phosphate, trace elements and organic acids was also studied. This study investigated effects of the Ag-np on hippocampal synaptic plasticity and spatial cognition in rats and followed with the research on their possible mechanism. Effect of Stay-Green Wheat, a Novel Variety of Wheat in China, on Glucose and Lipid Metabolism in High-Fat Diet Induced Type 2 Diabetic Rats. In this paper, we develop a mechanics-based dynamic model for bevel-tip flexible needle insertion into soft tissues. The use of a single ITA was beneficial on cardiac-related survival in all age groups, including octogenarians, compared to patients receiving only vein grafts. An Update on Ocular Surface Epithelial Stem Cells: Cornea and Conjunctiva.

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In a model of insulin resistance, MacT3 mice were more glucose tolerant and insulin sensitive than wild-type mice in both in vitro and in vivo tests. Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. NO-synthase activity products and respiratory tract inflammation: metabolism, pathophysiological role in allergic diseases. Hypoplastic left heart syndrome with left ventricular myocardial sinusoids: echocardiographic and angiographic findings in the first neonate surviving the Norwood I and II procedure. The patients were analyzed according to whether or not they received antifungal therapy, which was administered at the discretion of the attending physician. Although these diseases are relatively uncommon, dental practitioners should be familiar with the oral sequelae of these conditions and their management. Case of lung edema occurring as a result of inhalation of fumes from a Teflon-coated flying pan overheated for 4 hours. Aneurysms occur in large arteries and are characterized can zithromax treat urinary tract infection by pathological widening of the vessel and thinning of the vessel wall.

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