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Alfacip (Calcitriol)
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Alfacip

Alfacip is a synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Alfacip regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth. Alfacip receptor-binding protein appears to exist in the mucosa of human intestine.

Other names for this medication:
Actical, Alcee, Alfacalcirol, Alfacip, Alfarich, Arachitol, Aristrol, Biocitral, Bonestat, Calasto, Calbec, Calbovic, Calcibest, Calcicare, Calcigra, Calcikind, Calcimet, Caldikind, Calfa, Calotec, Calsure, Caltin, Caltop, Carcal, Denscal, Estovon, Ikmag, Kurecal, Laretol, Nutribone, Ostonex, Ostriol, Politrol, Primacal, Qpcal, Rical, Riecal, Rolsical, Romical, Solbiocal, Statbone, Tobalt, Trolec

Similar Products:
Benicar, Acticin, Colospa, Mestinon, Minocin, Exelon, Coreg

Also known as: Calcitriol

Description

Generic Alfacip is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfacip are intestine and bone. Generic Alfacip receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfacip may also act on the kidney and the parathyroid glands. Generic Alfacip is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfacip has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfacip, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfacip in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfacip produces other independent beneficial effects. Alfacip is also known as Calcitriol. Generic Alfacip treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfacip is Calcitriol. Brand name of Generic Alfacip is Alfacip.

Dosage

Generic Alfacip is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfacip suddenly.

Overdose

If you overdose Generic Alfacip and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfacip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alfacip if you are allergic to Generic Alfacip components. Do not take Generic Alfacip if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Alfacip if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Alfacip taking suddenly.

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In this review we examine the modifying effect of specific drugs on apoptosis. Imatinib is effective and safe in Korean patients with metastatic or unresectable GIST. The two most commonly used coping mechanisms that emerged from this study were psychological coping strategies (cognitive, behavioural and emotional) and social coping strategies (religious, social and professional support). We estimated the prevalence of zinc deficiency in Latin America, Africa and Asia, where based on zinc availability in the diet and childhood stunting rates, zinc deficiency is widespread. The rate of disappearance of CDDP in various media at 37.0 degrees C was studied using this method. This parameter is of interest in planning and dimensioning the provision of healthcare services. One way ANOVA was used for multiple group comparisons and Chi-square test was used for analyzing categorical data. Production of bacteriocin-like substances by lactic acid bacteria isolated from regional ovine cheese. Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. More importantly, knockdown of CDK6 partially abrogates gas5-siRNA-induced cell proliferation.

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Three-point bending tests were conducted on each sample according to the ISO 9693. SUBECTS AND METHODS: An investigation of 514 patients with prelingual deafness and 117 controls with normal hearing was conducted. Here we show that the mutated, cleavage-resistant form of CD40L is a more potent inducer of apoptosis than wild-type ligand in CD40-positive carcinoma cell lines. Housing first reduces re-offending among formerly homeless adults with mental disorders: results of a randomized controlled trial. The number of patients with gastroenteritis more than doubled six weeks before the Giardia epidemic was recognized. The present study investigated the changing pattern of antibiotic resistance and its effects on the clinical outcome in treating SBP. It could be speculated that ROS release, pro-inflammatory cytokines production and NF-kappa-B activation may play a key role. A questionnaire survey of patients discharged after laparoscopic surgery was performed to investigate and analyze the recovery of activity of daily living (ADL) 1 month after surgery. 12 were interpreted as supravesical, 11 as vesical bacteriurias. The estimates were substantially higher when maternal effects, either genetic or environmental, were ignored in the model.

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First, the influence of determinants on the waiting times of chronically ill patients in the ambulatory sector is investigated. Kinetics of indomethacin degradation II: Presence of alkali plus surfactant. While less potent than telithromycin (2) and paralleling the observations made in the previous study of 4,10-didesmethyl analogue (4), the inclusion of a single methyl group improves biological activity thus supporting its role in antibiotic activity. Excessive brain volume loss over time in cannabis-using first-episode schizophrenia patients. The clinical course, technical treatment aspects, and follow-up are described. Ultra-high performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry for the analysis of benzimidazole compounds in milk samples.

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However, perfusion of tau at concentrations approximately 20-fold higher than physiological levels showed no effect on FAT. As our understanding of the complex endocrine control that regulates metallothionein gene expression increases, a wider appreciation of a functional role(s) is emerging. SHARC NMR can be applied without any previous knowledge of the chemical shift distribution, but can be further optimized on the basis of a quick overview spectrum. Blood samples were obtained before every infusion and T-lymphocyte subsets were characterized by flow cytometry. Revision arthrodesis of the joint, as well as another attempt at percutaneous grafting had failed. Moderate and significant phenotypic correlations were found among reading, inattention and IQ, but not between impulsivity and the other variables. Hyperplastic alveolar epithelial cells were a prominent source of cytokines, where IL-10, PDGF-BB and KGF were present in increased amounts, although increased accumulation in fibroblasts, smooth-muscle cells and matrix components was also observed (PDGF-BB, TGF-beta). For a well-studied pair, these differences appear to be largely determined by the identity of a single residue at position 105 (leucine/GPR and glutamine/BPR). The aim of the present study was to evaluate the efficacy of an absorbable polylactic acid film barrier in preventing postoperative intra-abdominal adhesions, inflammation, and fibrosis in an animal model.

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Here, we observed an unusual discrepancy between MALDI-MS/MS and ESI-MS/MS on the methylation of trimethyllysine-containing peptides with residues 9-17 from human histone H3 and residues 73-83 from yeast histone H3. None of the patients had orthognatic surgery or alveolar bone grafting. Mention is made of other antiglaucoma medications used alone and in combination with topical beta-blockers. Sixty-eight women (mean age 81.9 years) from the latest visit of the Study of Osteoporotic Fractures who were concurrently measured with PSG and actigraphy. The recent increased detection of acetic acid bacteria as symbionts of other insect model organisms, such as Anopheles stephensi (G. The expression of these transcripts in unfed insects as well as blood fed insects was evaluated using real-time quantitative PCR. Mixed-type ADs abolished normal walking and sitting and induced unsteady walking, rigid lying, and a substantial number of WDS.

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These measures did not differ between TSA and hemiarthroplasty patients. Diseased bone extends beyond the limits of the bone exposed in the oral cavity. In a second experiment using a procedure that induces inhibition automatically schizophrenic patients showed levels of inhibition comparable to those of normal controls. All subjects received assigned treatment, panic-focused psychodynamic psychotherapy or applied relaxation training in twice-weekly sessions for 12 weeks. New apatite layer formed easily on the coated film when incubating in DPBS solution at 37 degrees C. Two patients had chronic diarrhea caused by nodular lymphoid hyperplasia, we showed two cases of granulomatous: spleen tuberculosis and pulmonary sarcoidosis. Design of an amphiphilic polymer for nanoparticle coating and functionalization. Upon stimulation of the cell recipient, the GFP was produced and evaluated by flow cytometry.

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Organic molecule-modulated phase evolution of inorganic mesostructures. Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division. A kinetic study of the phospholipase A 2 (Crotalus adamanteus) catalyzed hydrolysis of 1,2-dibutyryl-sn-glycero-3-phosphorylcholine. Tissue must be added to the thumb envelope from outside the contracted areas. Share epitope, citrullinated cyclic peptide antibodies and smoking in Brazilian rheumatoid arthritis patients. At the same time there were increases in the concentration of carnitine, and expression of OCTN2 and hormone-sensitive lipase (HSL) in the utero-tubal junction.

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Thallium-technetium subtraction scintigraphy not only successfully localized the parathyroid adenoma but also revealed the existence of an autonomous nodule of the thyroid, which was not suspected. Embryonic rat hippocampal neurons were cultured for 21 days and exposed to lead chloride beginning on the fourth day of incubation. After having once rejected in the course of search for sugar the cup with salt, the mice did not as a rule inspect it the second time, as is usually done by melliferous bees. The Genetical Analysis of Characters with Continuous Variability on a Mendelian Basis. We investigated the relation between the endothelin system and atrial fibrillation.

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From these results, and from other genetic and biochemical lines of evidence which suggest that replication of M dsRNA requires the presence of L-A dsRNA, we propose that the primary effect of the pet18 mutation is on the L-A VLP structure and that the inability of pet18 mutants to maintain M dsRNA comes from the loss of L-A dsRNA. A biomechanical study of simulated femoral neck fracture fixation by cannulated screws: effects of placement angle and number of screws. TNF-alpha regulates vascular smooth muscle cell responses in genetic hypertension. Because SDOP-DB is fully compliant with international standards, it can act as a practical foundation for international sharing and integration of mouse phenotypic information. Initially, PPARs were identified as regulators of gene expression in lipid metabolism and adipogenesis, but recent work has demonstrated PPAR expression in vascular cells and suggests antiinflammatory properties in the vasculature. The preliminary results seem to indicate that electrostimulation probably has a place in respiratory rehabilitation. The current status of isoform-specific inhibitor development is analyzed, especially inhibitors of HDAC1, 2, 4 and 8 enzymes, and the potential clinical utility of these compounds is discussed. Comparison of septal and hypothalamic self-stimulation during hypoxia. More importantly, they can selectively extravasate in tumor tissues due to its abnormal vascular nature. Inbreeding depression for size but not for symmetry in Drosophila melanogaster.

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Robust thermophysics-based interpretation of radiometrically uncalibrated IR images for ATR and site change detection. Since 1979 the continuous ambulatory peritoneal dialysis (CAPD) is used even in childhood. Serralysins are generally thought to function as pathogenicity factors of bacteria, but so far no hard evidence of this (e.g., specific substrate proteins that are sensitive to the cleavage by these proteases) has been found. Remodeling is a continuous process of skeletal destruction and renewal, occurring throughout life in humans and some other mammals. The identified candidate biomarker genes for cervical cancer represent several types of mechanisms in the cellular machinery that are epigenetically deregulated by hypermethylation, such as membrane receptors, intracellular signaling and gene transcription. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as novel or familiar and water as neutral gustatory stimulus. As nitrogen containing compounds, these substances increase the nitrogen load in wastewater. In contrast, recent studies have proposed that sensory integration of speech occurs at a coarser grain, approximate to the syllable, on the basis of indirect and relatively insensitive perceptual measures. Expression of nm23 was studied immunohistochemically, followed by amplification and direct sequencing of exons 4 and 5 of the nm23 gene.

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Caspase 3 was associated with the apoptotic pathway in human RPE cell death. In each instance, a deep pelvic/leg vein thromboembolus was associated with the dislodged filter. Determination of renal porphyrin handling in rats suffering from different kinds of chronic renal failure (CRF): uranyl nitrate (UN) induced fibrosis or 5/6-nephrectomy (5/6NX). The indication, problems and performance of puncture and marking methods in breast tumors are discussed and a new relief procedure for breast tumor diagnosis, involving peritumoral X-ray contrast medium injection, is described. There were 41 treatments in the first iteration, 42 in the second, and 34 in the final iteration. The regenerated plants had phenotypic characteristics typical to the transformed plants. A classical dichotic listening task paradigm was employed to assess event-related EEG potential (ERPs) indicators of selective attention as well as preattentive processing of mismatch, without interference by motor impairment.A total of 20 patients with sporadic ALS according to the revised El Escorial criteria and 20 healthy controls were studied.

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A study was undertaken to determine recurrence patterns and survival outcomes of stage I uterine papillary serous carcinoma (UPSC) patients. Moreover, it provides a unifying perspective for biophysical charge-transfer processes and helps to frame new questions associated with energy harvesting and transduction in fluctuating media. The research, planning, implementation, and evaluation of school-based mental health clinics located throughout a large metropolitan city, which were established in a joint project by four local mental health centers. The network simulation also displays color induction and assimilation behavior consistent with human perceptual data. By gradually increasing the erythromycin concentration of the medium and testing different membrane protein targets, we obtained a number of evolved strains of which four (NG2, NG3, NG5 and NG6) were characterized and their genome was fully sequenced. Testing for Mycoplasma pneumoniae antigen in a passive cutaneous anaphylaxis study. Second language listening difficulties perceived by low-level learners. These findings suggest a stepwise process via an intermediate capable of lactone closure with either stereochemistry, vasotec 20 mg side effects in contradistinction to the more familiar scenario in which anti addition is dictated by a bridging chloronium ion intermediate. Thus, consistent with previous crystallographic studies, formation of the glycosyl-enzyme intermediate leads to only localized structural changes.

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Preclinical studies suggest that differential brain monoamine neuromodulation is associated with impulsive decision-making and risk-taking behaviors. Identification of major common extracellular proteins secreted by Aeromonas salmonicida strains isolated from diseased fish. Allowance for the Coulombic electrostatic interactions is a prerequisite for accurate and reliable determination of lipid membrane-water partition coefficients of ionizable drugs from potentiometric titration data. Our observations support a new role for L1 or L1 ligands in neural precursor cell proliferation and differentiation. leprae infected animals, comparable to the observation made in human leprosy. In this article, professional coaching skills are presented that show how to regain the quality of the physician-patient relationship. A cellular subtype, which is though to be the origin of tumours as well as their malignant properties (i.e., capacity for regrowth and metastasis), are the cancer stem cells (CSCs).

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The inhibition of HSP90 downregulated B-Raf, decreased cell proliferation, and reduced activation of MEK/ERK in uveal melanoma cell lines expressing WT B-Raf. Because of the vast number of amino acids, various separation methods have been applied taking into consideration the large differences in their chemical structures, which span from nonpolar to highly polar side chains. The combined therapy of spinal balancing and the intervention of pathway of qi achieves the superior efficacy on various types of cervical spondylosis as compared with the conventional acupuncture and massage therapy. Furthermore, differences in protonix medication usage apelin and APJ expression have been described in patients with congestive heart failure and circulating levels of apelin are also reported to change in heart failure. However, various cases will arise when this will not remedy the retention and more aggressive measures will be needed, particularly if emergent urological consultation is not available. Drug-induced immune pancytopenia is considered an uncommon disorder. This ex vivo study suggested that ascorbic acid is helpful to ameliorate arsenic-induced oxidative stress. The staircase test consisted of placing a mouse in an enclosed staircase with 5 steps and recording (1) the number of steps and (2) rearings made during 3 min. Nociceptin (known also as orphanin FQ) is the most recently discovered member of the endogenous opioid peptide family, albeit nearly 15 years ago.

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This review discusses the altered respiratory mechanics in COPD, ways to detect these changes in a ventilated patient and formulating ventilatory techniques to optimize management of respiratory failure due to exacerbation of COPD. Children and adolescents appear to play an important role in the transmission of influenza. Hyperparathyroidism may cause a hyporegenerative anemia, the mechanisms for which have not been elucidated. 1-alpha-Hydroxyvitamin D3 in the management of primary hyperparathyroidism with bone disease. Radionuclide imaging of neurendocrine tumors: biological basis and diagnostic results. Therefore, patients with JIA can be vaccinated safely and effectively with the MenC conjugate.

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The optimum use of emulsifiers depends on our knowledge of their interfacial physico-chemical characteristics - such as surface activity, amount adsorbed, structure, thickness, topography, ability to desorb (stability), lateral mobility, interactions between adsorbed molecules, ability to change conformation, interfacial rheological properties, etc. Although A16886A has been chemically synthesized from deacetylcephalosporin C, this reaction could not be demonstrated with S. The patients, usually female, share certain described personality characteristics. In contrast, all examined cases of embryonal tumors (medulloblastoma and S-PNET), the most frequently diagnosed malignant brain tumors in childhood, showed no or trace CB2 immunoreactivity. Watson, and this interview aims at capturing the personality of the founder of American behaviorism through the eyes of his son, James B. Lepeophtheirus salmonis and Caligus elongatus are important parasites of wild and cultured salmonids in the Northern Hemisphere. A nutritional team is not essential for optimal parenteral nutrition therapy.

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The independent prognostic value of elevated jugular venous pressure or a third heart sound in patients with heart failure is not well established. Almost all patients with other muscle diseases and those with neural atrophy had modest elevations in pyruvate kinase activity. We hope these findings will guide future efforts to measure transmission parameters and to guide malaria control efforts. It dea drug schedule xanax was further demonstrated that purified COMP was cleaved by ADAMTS-4, but not ADAMTS-1 or -5, to yield a fragment which co-migrated with Fragment-110. Implementation of a QC programme is a continuous and complex process. Prospective data collection of their subsequent course took place in 2001.

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Sources and pathways of 90Sr in the North Atlantic-Arctic region: present day and global warming. Thickness of the gallbladder wall in patients with hypoalbuminemia: a sonographic study of patients on peritoneal dialysis. Histopathological examination confirmed diagnosis of NEC in the involved bowel and controls showed appearance within normal limit. Impact of HDL on adipose tissue metabolism and adiponectin expression. There is no widely accepted definition, although it is beyond dispute that comfort and discomfort are feelings or emotions that are subjective in nature. Development of a Tc-99m labeled sigma-2 receptor-specific ligand as a potential breast tumor imaging agent. Ventral cysts are more likely to cause weakness and myelopathic signs. The aim of the present study was to investigate depression in relation to gender and age in the general adult population. Nonviral gene therapy requires a high yield and a low cost production of eukaryotic expression vectors that meet defined criteria such as biosafety and quality of pharmaceutical grade.

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Families showing a low genetic stability during establishment of coreg cr 80 mg embryogenic cultures had a higher embryogenic potential than those which were genetically more stable. Despite the high death rate in RAs, there was a downward trend in mortality in RAs over the study period. These endpoints may reflect the presence of different types of persistent DNA-damage. Influence of carbon dioxide supply on the chloroplast structure of Chlorella pyrenoidosa. Prevalence of anemia in pregnant women and its effect on neonatal outcomes in Northeast India. Domestic accidents: a study on children attending the emergency department of the city of Padua.

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However, if the colour was not immediately task relevant, it failed to interact with perceptual selection. Imipramine and phenylephrine but not clonidine, yohimbine or prazosin decreased locomotion. Autonomic what kind of blood pressure medicine is norvasc alterations in cocaine-exposed neonates following orthostatic stress. The risks for osteoporosis, as reflected by low bone density, and the risks for fracture overlap but are not identical. Glycosylation of rat albumin in vitro led to an increase in its ability to increase polymerization lag time, but the concentration of albumin required was greater than that found in the serum fractions. The main symptom is a permanent wilting of the plant aerial parts. The burden of motorcycle-related neuro-trauma in Ireland and associated helmet usage. However, the K(m) of cAMP for the W1072A mutation was only increased by about 7-fold.

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