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Alfabond (Calcitriol)
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Alfabond

Alfabond is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Alfabond is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Actical, Alfabond, Arachitol, Arcium, Aristrol, Biocitral, Calbec, Calbory, Calcimet, Calcirol, Calcor, Caldikind, Calfa, Calgel, Calotec, Caltin, Dmcal, Duracal, Lctrol, Novadee, Nutribone, Rical, Riecal, Ritoca, Rockbon, Roical, Rolsical, Statbone, Sunmic, Vezocal, Vitalpha

Similar Products:
Dulcolax, Calan, Diflucan, Elocon, Compazine, Geodon, Nolvadex, Omnicef, Albenza, Keflex

Also known as: Calcitriol

Description

Generic Alfabond is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfabond are intestine and bone. Generic Alfabond receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfabond may also act on the kidney and the parathyroid glands. Generic Alfabond is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfabond has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfabond, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfabond in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfabond produces other independent beneficial effects. Alfabond is also known as Calcitriol. Generic Alfabond treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfabond is Calcitriol. Brand name of Generic Alfabond is Alfabond.

Dosage

Generic Alfabond is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfabond suddenly.

Overdose

If you overdose Generic Alfabond and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfabond are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alfabond if you are allergic to Generic Alfabond components. Do not take Generic Alfabond if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Alfabond if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Alfabond taking suddenly.

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In accordance with experimental data, TIP4P/2005 predicts a minimum in the shear viscosity for the 273 K isotherm, a shift in the minimum toward lower pressures at 298 K, and its disappearance at 373 K. Interleukin-4 (IL-4) is a CD132-dependent cytokine known to activate the Jak-STAT pathway in different cells and cell lines. This can be achieved using a single agent that inhibits multiple signaling pathways or a combination of highly selective agents. Taking and preserving of test materials for clinical chemical studies. Filariasis is an endemic disease in tropical and subtropical countries. Radiological evaluation revealed enhancing lesions involving both thalami. All enzyme complexes synthesized DNA on single-stranded (ss) DNA and replicated simian virus 40 DNA. The study included preoperative and intraoperative data on 2950 patients. Thrombophilia due to mutations in genes encoding coagulation factor V (G1691A), prothrombin (G20210A), methylene-tetrahydrofolate reductase (C677T) and the presence of antiphospholipid antibodies was searched for.

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Effects of methylphenidate hydrochloride on the cardiovascular system in vivo and in vitro: a safety pharmacology study. Osteoclast activity was studied on nacre, the mother of pearl (MOP) in order to assess the plasticity of bone resorbing cells and their capacity to adapt to a biomineralized material with a different organic and mineral composition from that of its natural substrate, bone. These systems consist of dendritic structures based on Boltorn H20 and H30 hyperbranched polymers to which carbohydrates are linked through a convenient spacer. Progenies of the warm parental environment showed faster germination rates, faster root elongation growth, higher leaf biomass and increased seed production at various temperatures compared with those from the cold parental environment. Third-generation, single-molecule sequencing addresses this problem by greatly increasing sequencing read length, which simplifies the assembly problem. Intensive muscular exercise has been reported to modify serum iron parameters and to increase hepcidinuria. Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality. Static visual field perimetry with Octopus 101 perimeter is more sensitive than Goldmann perimetry in the early diagnosis of pituitary adenomas. Perturbations to hip movement were applied either by 1) manual resistance or assistance to swing or by 2) resistance to hip flexion using a device that blocked hip flexion but allowed leg extension.

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The potential of stem cell therapy for osteoarthritis and rheumatoid arthritis. Prolactin may promote type 1 T cell infiltration into psoriatic lesions via these chemokines. The adaptive optics technology may be of clinical benefit when counseling patients with highly aberrated eyes regarding their maximum subjective potential for vision correction. Development of UV/HPLC methods for quantitative analysis of benznidazole in human plasma and urine for application in pediatric clinical studies. Effectiveness of acupuncture for nonspecific chronic low back pain: a systematic review and meta-analysis. This study shows that the main function of the gills is excretory and describes three apparent systems whereby excretory products and necrotic coelomocytes are removed.

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1-Deoxy-D-xylulose 5-phosphate reductoisomerase and plastid isoprenoid biosynthesis during tomato fruit ripening. CD33-related sialic-acid-binding immunoglobulin-like lectins in health and disease. The interaction between the histidine-containing phosphocarrier protein HPr and xenon atoms in solution is studied in the present paper. The SRS-22-fv showed satisfactory reliability, factorial, concurrent, and discriminant validity. This qualitative study examined the interactional communication strategies used by law enforcement officers during a hostage-taking incident at a high school. On the number of stable equilibria and the simultaneous stability of fixation and polymorphism in two-locus models. This complex can preferentially recognize UV-damaged DNA over undamaged DNA and has been implicated in the stabilization of open complex formation during nucleotide excision repair.

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Here we show that Rab7, a small GTPase that is associated with late endosomes, is highly expressed and is predominantly localized at the ruffled border in bone-resorbing osteoclasts. A simple device for analogue recording of the abundance of selected ions from a combined gas chromatograph-mass spectrometer. Blood circulation was measured with a laser Doppler flowmeter, and flap survival lengths were recorded. Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Subjective precose drug class response to neuroleptic medication: a validation study of the Italian version of the Drug Attitude Inventory (DAI).

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