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Alfabond (Calcitriol)

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Alfabond is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Alfabond is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Actical, Alfabond, Arachitol, Arcium, Aristrol, Biocitral, Calbec, Calbory, Calcimet, Calcirol, Calcor, Caldikind, Calfa, Calgel, Calotec, Caltin, Dmcal, Duracal, Lctrol, Novadee, Nutribone, Rical, Riecal, Ritoca, Rockbon, Roical, Rolsical, Statbone, Sunmic, Vezocal, Vitalpha

Similar Products:
Dulcolax, Calan, Diflucan, Elocon, Compazine, Geodon, Nolvadex, Omnicef, Albenza, Keflex

Also known as: Calcitriol


Generic Alfabond is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfabond are intestine and bone. Generic Alfabond receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfabond may also act on the kidney and the parathyroid glands. Generic Alfabond is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfabond has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfabond, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfabond in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfabond produces other independent beneficial effects. Alfabond is also known as Calcitriol. Generic Alfabond treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfabond is Calcitriol. Brand name of Generic Alfabond is Alfabond.


Generic Alfabond is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfabond suddenly.


If you overdose Generic Alfabond and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfabond are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Alfabond if you are allergic to Generic Alfabond components. Do not take Generic Alfabond if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Alfabond if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Alfabond taking suddenly.

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In accordance with experimental data, TIP4P/2005 predicts a minimum in the shear viscosity for the 273 K isotherm, a shift in the minimum toward lower pressures at 298 K, and its disappearance at 373 K. Interleukin-4 (IL-4) is a CD132-dependent cytokine known to activate the Jak-STAT pathway in different cells and cell lines. This can be achieved using a single agent that inhibits multiple signaling pathways or a combination of highly selective agents. Taking and preserving of test materials for clinical chemical studies. Filariasis is an endemic disease in tropical and subtropical countries. Radiological evaluation revealed enhancing lesions involving both thalami. All enzyme complexes synthesized DNA on single-stranded (ss) DNA and replicated simian virus 40 DNA. The study included preoperative and intraoperative data on 2950 patients. Thrombophilia due to mutations in genes encoding coagulation factor V (G1691A), prothrombin (G20210A), methylene-tetrahydrofolate reductase (C677T) and the presence of antiphospholipid antibodies was searched for.

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The highest incidents rate of mumps 52.0/100,000 was recorded among children at the age 5-9 years of age. burnetii is one of the most commonly recognized pathogens among community-acquired pneumonias in Western countries, but in Japan, reports of community-acquired C. A rhytidectomy approach to the parotid gland seems to be safe method and aesthetic results are more satisfactory as comparing to classical approach. According to character of cyanide natural degradation in soil the measurement of prevention and cure soil pollution by goldmine tailing dam collapsing was brought forward. Magnetic resonance imaging showed a focally expansile, intramedullary lesion at L1-2 levels with exophytic component, which was located at the apex of diplomyelia separating the cord into equal hemicords and low-lying spinal cord ending at L3 level. Executive functions (EF) give support for organization, anticipation, inhibition, working memory, flexibility, control and autoregulation of behavior. To measure the functional relatedness of a gene set, these measures consider every pair of genes in the set, and the average of all pairwise distances is calculated. Twelve months after surgery, the cat had no special dietary requirements and remained clinically normal. Calcium-dependent gene regulation in myocyte hypertrophy and remodeling.

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Effects of methylphenidate hydrochloride on the cardiovascular system in vivo and in vitro: a safety pharmacology study. Osteoclast activity was studied on nacre, the mother of pearl (MOP) in order to assess the plasticity of bone resorbing cells and their capacity to adapt to a biomineralized material with a different organic and mineral composition from that of its natural substrate, bone. These systems consist of dendritic structures based on Boltorn H20 and H30 hyperbranched polymers to which carbohydrates are linked through a convenient spacer. Progenies of the warm parental environment showed faster germination rates, faster root elongation growth, higher leaf biomass and increased seed production at various temperatures compared with those from the cold parental environment. Third-generation, single-molecule sequencing addresses this problem by greatly increasing sequencing read length, which simplifies the assembly problem. Intensive muscular exercise has been reported to modify serum iron parameters and to increase hepcidinuria. Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality. Static visual field perimetry with Octopus 101 perimeter is more sensitive than Goldmann perimetry in the early diagnosis of pituitary adenomas. Perturbations to hip movement were applied either by 1) manual resistance or assistance to swing or by 2) resistance to hip flexion using a device that blocked hip flexion but allowed leg extension.

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The potential of stem cell therapy for osteoarthritis and rheumatoid arthritis. Prolactin may promote type 1 T cell infiltration into psoriatic lesions via these chemokines. The adaptive optics technology may be of clinical benefit when counseling patients with highly aberrated eyes regarding their maximum subjective potential for vision correction. Development of UV/HPLC methods for quantitative analysis of benznidazole in human plasma and urine for application in pediatric clinical studies. Effectiveness of acupuncture for nonspecific chronic low back pain: a systematic review and meta-analysis. This study shows that the main function of the gills is excretory and describes three apparent systems whereby excretory products and necrotic coelomocytes are removed.

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1-Deoxy-D-xylulose 5-phosphate reductoisomerase and plastid isoprenoid biosynthesis during tomato fruit ripening. CD33-related sialic-acid-binding immunoglobulin-like lectins in health and disease. The interaction between the histidine-containing phosphocarrier protein HPr and xenon atoms in solution is studied in the present paper. The SRS-22-fv showed satisfactory reliability, factorial, concurrent, and discriminant validity. This qualitative study examined the interactional communication strategies used by law enforcement officers during a hostage-taking incident at a high school. On the number of stable equilibria and the simultaneous stability of fixation and polymorphism in two-locus models. This complex can preferentially recognize UV-damaged DNA over undamaged DNA and has been implicated in the stabilization of open complex formation during nucleotide excision repair.

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Gastric cancer cells MKN45 were synchronized at G2/M and G1/S point by nocodazole-thymidine and double thymidine methods. Also, nerve growth factor (NGF) content was measured in bladder and dorsal root ganglia (DRG). Cardiac index, stroke index, and systemic vascular resistance index were calculated. Reporting six cases of posterior dislocation of the shoulder examined in a rheumatological setting, the authors emphasize the diagnostic difficulties in this condition. We should, therefore, carefully select our patients for treatment with the NOA with an emphasis on age, body weight, renal function and comedications and follow them faithfully concerning their medication adherence and eventual side effects. Development of a brief mental health screen for intimate partner violence victims in the emergency department. Compared with SIMV, NAVA appears to improve patient-ventilator synchrony, decrease PIP, and reduce diaphragmatic muscle load and work of breathing in preterm infants with RDS during mechanical ventilation. The interactions between Txe-Asp83Tyr and YefM were sufficiently strong to abolish Txe toxicity and to allow effective corepression by YefM-Txe-Asp83Tyr of the promoter from which yefM-yoeB is expressed. Calmodulin levels in developing muscle tissues and primary cultures of normal and dystrophic (UM-X7.1) hamsters.

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The cause of death was certified as sudden infant death syndrome after full investigation, and all autopsy studies were negative. What is known about the organization and function of these loops is generally consistent with the results obtained by stimulating or lesioning or injecting drugs into the mPFC, yet these findings are largely inconsistent with the functional organization of the mPFC-NAS projection. The study produced a definition of narrative research which allows such work to be distinguished can i buy zantac otc from the non-research use of stories in health care, and preliminary quality standards for evaluating narrative research. Entomological surveys showed a reduction in numbers of female Phlebotomus sergenti captured indoors in intervention sectors. Infrared absorption bands of alpha and beta -pinenes in the 8-14-microm atmospheric window region. IPD is a serious disease with a high complication rate and mortality.

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Here we show that Rab7, a small GTPase that is associated with late endosomes, is highly expressed and is predominantly localized at the ruffled border in bone-resorbing osteoclasts. A simple device for analogue recording of the abundance of selected ions from a combined gas chromatograph-mass spectrometer. Blood circulation was measured with a laser Doppler flowmeter, and flap survival lengths were recorded. Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Subjective precose drug class response to neuroleptic medication: a validation study of the Italian version of the Drug Attitude Inventory (DAI).

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The purpose of this study was to compare the effects of crystalloid and crystalloid-colloid solutions administered at different times after isolated traumatic brain injury. These results suggest that although the manifestation of effectiveness may be delayed by changes in networks of neurotransmitters related to the nociceptive pathways following nerve injury, longer-term repetitive application of capsaicin cream has a significant therapeutic effect on subjects with painful peripheral neuropathy. Effects of diltiazem on electrical and mechanical activities of isolated guinea pig taenia coli. Using integrated EMG measures, we tested three hypotheses for each muscle: (1) there would be no difference in muscle activity between the residual and intact legs, (2) there would be no difference in muscle activity between the intact leg and non-amputee legs, and (3) muscle activity in the residual and intact legs would increase with speed. There are 6.0 amino acids/nucleotide in HMG1-bound DNA and 5.0 in HMGI-bound DNA which suggests that each HMB1 moleculae would cover about 20 base pairs of DNA and each HMG2 molecule would cover about 25 base pairs. To do this, we must understand the rationale for recommending interventions, the biological pathways by which interventions work, delivery systems required to make efficacious interventions work, and other contextual factors that might limit or facilitate successful implementation. Nine patients underwent right-lobe liver resection for adult living related liver transplants between October 1999 and September 2000. The receptor-mediated response by IL-17A significantly up-regulated IL-6 release alone in the non-eosinophilic and eosinophilic groups as compared with the control group. Social dominance orientation and gender: the moderating role of gender identity.

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