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Afineday (Montelukast)
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Afineday

Afineday works by reducing and preventing swelling and inflammation in your lungs. It is known as a “preventer” and is used to prevent the symptoms of asthma such as tightness in your chest, wheezing, breathlessness and coughing.

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Also known as: Montelukast

Description

Afineday tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.

Dosage

Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Afineday should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Afineday should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Afineday should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Afineday dose daily in the evening. Pediatric patients are advised to take chewable tablets.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Afineday are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take the Afineday if you are allergic to Montelukast or any of the other ingredients of this medicine. Do not use the tablets to treat an acute asthma attack, including Status Asthmaticus. Do not use the drug if you suffer from severe kidney failure. Do not combine the medication with drugs which induce the CYP450 enzyme system (phenobarbital and rifampin), as they may decrease the effects of Montelukast. Do not use the medication if you have a phenylketonuria, as Afineday contains phenylalanine. Do not take the medication tablets during pregnancy or while breastfeeding without consulting your doctor. Avoid drinking alcohol while taking Afineday tablets, as it may cause excessive drowsiness. Do not give this medicine to children less than 2 years of age.

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The present study suggested that kerogen materials found in soils and sediments should not be treated as a single, unified, carbonaceous sorbent phase. The state-trait inventory was administered to screen symptoms of anxiety. A total of 9023 persons born throughout England, Scotland and Wales during 1 week in 1958 were followed periodically through childhood into adulthood. Linkage analysis and preliminary assessment of deleterious gene loads. Treatment of hepatic hydatid cyst in sheep by echographic puncture. Risk factors for both racial/ethnic groups were family mental illness, multiple moves, lack of parental warmth, lax supervision, and harsh punishment. Often times, routine treatment modalities are not adequate and the use of different management strategies is necessary. Diabetic retinopathy and diabetic nephropathy are common microvascular complications of diabetes. Because lipopeptide biosurfactants are known to enhance efficacy of bioactive compounds and arfA/B/C/D/E orthologous genes are also found in plant pathogenic P.

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Addition of prostanoids in pulmonary hypertension deteriorating on oral therapy. Adsorption of aqueous oil on sands and its studies of effective factors. These findings indicate that women originating from communities where FGM is normative live in a context in which the practice is viewed as an important aspect of life even after immigration. The increased expression of genes taking part in the inflammatory reaction (interleukin 6, granulocyte and macrophage chemotactic proteins) was observed from day 2. The present findings exemplify the role that atrazine and other endocrine-disrupting pesticides likely play in global amphibian declines. The majority of victims had chronic mental disorders, mainly schizophrenia, depression and substance abuse. Dopamine or SKF38393 (D1 receptor agonist) inhibited ionomycin (calcium ionophore)-induced toxicity, while dopamine did not affect S-nitrosocysteine (NO donor)-induced toxicity. When MSDO is suspected, a clinical endodontic examination should be performed to rule out or treat an odontogenic etiology. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) was used for metabolomic analysis imaging of frozen carotid atheroma plaques.

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This study examined the effects of inspiratory muscle training (IMT) with high-intensity inspiratory pressure loads on respiratory muscle performance and exertional dyspnea. The present study underlines the need for early intervention programs aimed at decreasing any tolerance for the use of violence in dating relationships of Spanish adolescents. Can non-monetary incentives increase health facility deliveries?. Amino-retinoid compounds in the human retinal pigment epithelium. Interleukin-1 family polymorphisms in aggressive periodontitis patients and their relatives. Anastomotic leakage and respiratory complications are among the most common and potentially life-threatening complications following the surgical repair of esophageal atresia. We then discuss various aspects of pimecrolimus, including pharmacologic properties, toxicology, short- and long-term studies, and safety and adverse events. These tests are sensitive to factors that both increase and decrease mental energy. The system of medical selection of Soviet cosmonauts stemmed from that used in aviation medicine, particularly medical expertise of the flying personnel. Serum somatomedin activity was found to be very low in cases of growth retardation and malnutrition due to congenital heart disease and to malabsorption, respectively.

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