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Adaferin (Adapalene)

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Adaferin and Adaferin (Retin-A) are different medications, but they are both used to treat mild-to-moderate acne. Adaferin contains adapalene, and Retin-A contains Adaferin. They both offer a range of benefits and options, so talk to your healthcare provider to discuss which one would be the best fit for you.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Adaferin, Adapalene, Adapen, Adaret, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep

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Ativan, Cipro, Minocin, Crestor, Azulfidine, Rebetol, Aldactone, Singulair, Lanoxin, Estrace

Also known as: Adapalene


Adaferin is a third-generation topical retinoid primarily used in the treatment of acne. Adaferin is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adaferin gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adaferin works under the skin surface to unclog pores and clear up pimples. Adaferin is also known as Adapalene, Adapen, Adaferin. Generic name of Adaferin is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Adaferin exactly as directed. Adaferin is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adaferin. Adaferin should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adaferin. Continue using Adaferin until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adaferin promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Adaferin and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adaferin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Adaferin if you are allergic to Adaferin components. It is not known whether Adaferin will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant or breast-feeding. Do not get Adaferin in your eyes or on the inside of your nose or mouth. For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using the medicine during this time. Do not use other medicines on your skin without first discussing it with your doctor. While you are using Adaferin, you may use cosmetics. After using cosmetics, thoroughly wash and dry the affected area before applying this medicine. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Adaferin. Use a sunscreen if you must be outside. Do not apply it to sunburned skin. Do not stop taking Adaferin suddenly.

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A broad array of composite nanoarchitectures can be designed and fabricated, involving generic materials such as metal, ceramics, and polymers in nanoscale form. The current acceptance, accessibility and recognition of Chinese and Ayurvedic medicine in the United States in the public, governmental, and industrial sectors. For a clinical trial with a time-to-event primary endpoint, the rate of accrual of the event of interest determines the timing of the analysis, upon which significant resources and strategic planning depend. Although KT height surrounding the dentition has been devalued by evidence-based studies, the value-added protection of KT height increase after decortication and augmentation bone grafting offsets the concerns of orthodontic proclination or expanding mandibular incisors facially. RSp1486a exhibited different substrate specificity from BsLal, and preferably synthesized hetero-dipeptides where more bulky amino acid was placed at N terminus and less bulky amino acid was placed at C terminus in opposition to those synthesized by BsLal. Computertomography of the kidney is, in combination with the conventional non-invasive methods, a highly exact diagnostic process. The new data document an important role of STAT3 in PI3K-driven oncogenic transformation and mark BMX as a promising therapeutic target that could enhance the effectiveness of PI3K inhibitors.

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