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Acnovate (Adapalene)

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Acnovate is a retinoid. While experts aren't exactly sure how it treats acne, they believe it works by stopping pimples from forming under the skin and lowering the amount of redness and inflammation on the skin.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Benemid, Evista, Coumadin, Ditropan, Micardis, Dostinex, Feldene, Cardura

Also known as: Adapalene


Acnovate is a third-generation topical retinoid primarily used in the treatment of acne. Acnovate is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Acnovate gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Acnovate works under the skin surface to unclog pores and clear up pimples. Acnovate is also known as Adapalene, Adapen, Adaferin. Generic name of Acnovate is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Acnovate exactly as directed. Acnovate is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Acnovate. Acnovate should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Acnovate. Continue using Acnovate until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Acnovate promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Acnovate and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acnovate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Acnovate if you are allergic to Acnovate components. It is not known whether Acnovate will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant or breast-feeding. Do not get Acnovate in your eyes or on the inside of your nose or mouth. For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using the medicine during this time. Do not use other medicines on your skin without first discussing it with your doctor. While you are using Acnovate, you may use cosmetics. After using cosmetics, thoroughly wash and dry the affected area before applying this medicine. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Acnovate. Use a sunscreen if you must be outside. Do not apply it to sunburned skin. Do not stop taking Acnovate suddenly.

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Tissular proteins and enzymes: a study by starch gel electrophoresis. To present our experience and outcomes with robotic mid and distal ureteral reconstruction and to compare these results with our previous laparoscopic series. The purpose of this study was to evaluate early predictive factors and long-term changes in intact parathyroid hormone (iPTH) levels in patients with transient and permanent hypocalcemia after total thyroidectomy. Then the anti-prohibitin autoantibodies were detected by western blotting by using rhPHB protein to incubate sera from patients with rheumatoid arthritis (RA). Transcriptional and epigenetic regulation is critical for proper heart development, cardiac homeostasis, and pathogenesis. All ceramic crowns made through three different veneering methods revealed clinically acceptable marginal fit.

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Prenatal exposure to 1.5-T MRI during the second or third trimester of pregnancy in a cohort of healthy fetuses is not associated with disturbances in functional outcomes or hearing impairment at preschool age. Sensitivity of DNA repair-deficient strains of Escherichia coli K-12 to various furocoumarins and near-ultraviolet radiation. Influence of ethanol extract of Ginkgo biloba leaves on the isolated rat heart work and mitochondria functions. To investigate the potential contribution of the PI3K, Rac1 and PAK1 to the development of EMPD. Conservative treatment of cystine calculi: effect of oral alpha-mercaptopropionylglycine on cystine stone dissolution and on prevention of stone recurrence. The evaluation results demonstrate that the Ontario Stroke System has had positive measurable impacts on access to stroke-related services, the integration and coordination of stroke care, treatment for stroke, and client and provider satisfaction.

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Exposure of Escherichia coli to the antibiotic mitomycin C (MTC) at a concentration of 0.5 mug/ml caused cross-linkage between complementary strands of deoxyribonucleic acid (DNA). Following reverse transcription, a large set of barcode sequences is added in excess, and nearly every cDNA molecule is uniquely labeled by random attachment of barcode sequences to both ends. The short SASEQ can easily be used in busy clinical practice to guide smoking cessation interventions. MicroRNA-133a functions as a tumor suppressor by targeting IGF-1R in hepatocellular carcinoma. Atrioventricular valves were analyzed longitudinally in STIC volumes of 74 normal fetuses between the 15th and 36th week of pregnancy. Female gout: age and duration of the disease determine clinical presentation. A proteomic analysis of Glb-RNAi seeds showed that the reductions in glutelin and prolamin were conserved at the protein level. To identify the rate of, and risk factors for, lower urinary tract (LUT) injuries associated with the transobturator tension-free vaginal tape (TOT) procedure.

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Multiparametric MR imaging (mpMRI) is defined as the integration of information from different morphological and functional datasets. The respiratory patterns define a point cloud near the lung region boundary representing a subjective contour. Targeting MKK7 rather than JNK could provide site and event specificity when treating synovitis. However, components of the classical complement pathway might be related to the deposition of IgG and IgM in the glomerulus. guianensis in a semi deciduous forest fragment in Brazilian Cerrado and measure which species have the highest potential as seed dispersers. Recently we have reported that BRCA1 regulates the transcription of several genes in prostate cancer, including ATM (ataxia telangiectasia mutated). It is well established that a large amount of natural and man-made chemicals are present in the environment and both humans and animals are exposed to them. The abundance of these proteins and their avid binding of bilirubin and its conjugates have encouraged investigation into their potential role in hepatic transport and metabolism of organic anions. NPs in the sample believed that pediatric overweight and obesity are problems in need of treatment, but also reported not assessing and diagnosing the condition per current guidelines.

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