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Aclene (Adapalene)

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Aclene works well for treating mild-to-moderate acne, but it can cause burning and itching right after using it. The medication has many different formulations, but only the lower strength gel is available over-the-counter.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Aurogra, Aldactone, Bystolic, Pamelor, Soma

Also known as: Adapalene


Aclene is a third-generation topical retinoid primarily used in the treatment of acne. Aclene is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Aclene gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Aclene works under the skin surface to unclog pores and clear up pimples. Aclene is also known as Adapalene, Adapen, Adaferin. Generic name of Aclene is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Aclene exactly as directed. Aclene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Aclene. Aclene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Aclene. Continue using Aclene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Aclene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Aclene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aclene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Aclene if you are allergic to Aclene components. It is not known whether Aclene will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant or breast-feeding. Do not get Aclene in your eyes or on the inside of your nose or mouth. For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using the medicine during this time. Do not use other medicines on your skin without first discussing it with your doctor. While you are using Aclene, you may use cosmetics. After using cosmetics, thoroughly wash and dry the affected area before applying this medicine. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Aclene. Use a sunscreen if you must be outside. Do not apply it to sunburned skin. Do not stop taking Aclene suddenly.

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This is the first attempt to quantify CO(2) emissions related to MIS in the United States. Combined modality therapy for rectal cancer: the relative value of posttreatment versus pretreatment CEA as a prognostic marker for disease recurrence. Quality measures for primary care of complex pediatric patients. The fibers in this basal part of the supraoptic nucleus as well as those of the internal zone of the median eminence, beside few polymorphic, positively strained granules, contain a labeled tubular network or free PAP on fuzzy material. Multiunit recording with a multi-electrode in the brain has been widely used in neuroscience studies. The Euphorbia factors I1, I5, and I6 are esters of ingenane-type poly-functional diterpene alcohols. Dance-related injuries in children and adolescents treated in US emergency departments in 1991-2007. STn-positive gastric cancer cells showed higher intraperitoneal metastatic ability in comparison with sTn-negative control, resulting in shortened survival time of the mice, which was mitigated by anti-sTn antibody administration. The aim of this study was to investigate whether whole-body vibration (WBV) is associated with prolapsed lumbar intervertebral disc (PID) and nerve root entrapment among patients with low-back pain (LBP) undergoing magnetic resonance imaging (MRI).

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Physical mapping of the 5S rDNA gene complex in rice (Oryza sativa). Despite inclusions that are elicited by different mechanisms depending on the specific neurotoxin, their ultrastructural features are similar and there is a high parallelism in their temporal evolution. Synthesis of the first poly(diaminosulfide)s and an investigation of their applications as drug delivery vehicles. Finally, c-Myb expression was markedly elevated in surgical specimens of GBMs compared with normal tissues. Supramolecular polymerization and polymorphs of oligo(p-phenylene vinylene)-functionalized bis- and monoureas. The usefulness of the oscillatory potentials in the prognosis of retinal disease, particularly in diabetic retinopathy, is reviewed. Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect. Available HbA1c lab results for up to 10 yr were collected from medical records at 67 T1D Exchange clinics. However, a new class of molecules in development for the active regulation and resolution of inflammation shows theoretical promise for the treatment of inflammatory lesions. This article reviews the rationale for the use of DHE in these common, often difficult-to-treat migraine forms.

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Renin-angiotensin mediation of adrenal catecholamine secretion induced by hypoglycaemia in the cat. We report the novel findings that JS-K amiodarone pulmonary toxicity review inhibits breast cancer invasion across the Matrigel basement membrane, and NO production is vital for this activity. Prognostic significance of pathologic changes of the rectal adenocarcinoma. A study was made of the influence of ablation of the entorhinal cortex on conditioned reflexes to present and trace stimuli. orbiculare expresses NIS1 at the postinvasive stage and suggest that NCD could be repressed via other effectors, including the CgDN3 homologue. The cross-sectional study was carried out on intravenous drug users who attended health and social care Drop-in centers during November 2008 to February 2009 in Isfahan province, Iran.

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